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Results for "
kds-2010
" in TargetMol Product Catalog- Inhibitors & Agonists3
Tisolagiline
KDS2010, KDS 2010
T781271894207-44-3
Tisolagiline (KDS2010) is a potent, highly selective and reversible MAO-B inhibitor with IC50=8 nM and oral activity for the treatment of Alzheimer's disease and obesity.
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KDS2010 mesylate
T700751894207-45-4
KDS2010 is a potent, highly selective, and reversible MAO-B inhibitor which shows 12,500-fold selectivity over MAO-A. KDS2010 overcomes the disadvantages of the irreversible MAO-B inhibitor and significantly attenuates increased astrocytic GABA levels and astrogliosis, thereby enhancing synaptic transmission, and rescuing learning and memory impairments in APP PS1 mice.
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