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By Tag- C-6xHis
- C-His(2)
- Tag Free(1)
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By Tag By Expression System- HEK293 Cells(3)
- E. coli(1)
- P. pastoris (Yeast)(1)
By Species- Human(3)
- Cynomolgus(1)
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By SPR-compatible Buffer- Ready-to-use(4)
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Results for "
joint destruction
" in TargetMol Product Catalog- Inhibitors & Agonists4
- Natural Products1
- Recombinant Protein5
CompareInterleukin-17A, IL-17A, IL17A, IL-17, IL17, Cytotoxic T-Lymphocyte-Associated Antigen 8, CTLA-8, CTLA8
TMPJ-01172
Expression system: HEK293 Cells
Length: 22-158, Partial
Activity: BLI、Cells
Length: 22-158, Partial
Activity: BLI、Cells
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CompareInterleukin-17A, IL-17A, IL17A, IL-17, IL17, Cytotoxic T-Lymphocyte-Associated Antigen 8, CTLA-8, CTLA8
TMPJ-01444
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. As IL-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumatoid arthritis synovium. It increases IL-6 production, induces collagen degradation and decreases collagen synthesis by synovium and cartilage and proteoglycan synthesis in cartilage. IL-17 is also able to increase bone destruction and reduce its formation. Blocking of interleukin-17 with specific inhibitors provides a protective inhibition of cartilage and bone degradation.
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CompareSCYL1, SCYA13, NCC-1, NCC1, MCP-4, MCP4, CKb10, chemokine (C-C motif) ligand 13, CCL13
TMPY-00564
Expression system: P. pastoris (Yeast)
Length: 24-98, Partial
Activity: Not Tested
Length: 24-98, Partial
Activity: Not Tested
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CompareYKL-39, YKL39, chitinase 3 like 2, CHIL2
TMPY-01933
Expression system: HEK293 Cells
Length: 1-390, Full Length
Activity: Not Tested
Length: 1-390, Full Length
Activity: Not Tested
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CompareRASI-1, MMP18, matrix metallopeptidase 19
TMPY-02965
Expression system: E. coli
Length: 101-256, Partial
Activity: Not Tested
Length: 101-256, Partial
Activity: Not Tested
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