hsert

Trimipramine maleate (Surmontil maleate) appears to inhibit serotonin transport and norepinephrine uptake by nerve terminals. This increases available norepinephrine or serotonin and prolongs its action. Trimipramine Maleate is the maleate salt form of trimipramine, a tricyclic secondary amine of the dibenzazepine class, with an antidepressant property.

H-Ser(tBu)-OH is an amino acid derivative and has a wide range of applications in life science related research.

H-Ser(tBu)-OtBu.HCl, an amino acid derivative, has a wide range of applications in life science-related research.

H-Ser(tBu)-OMe.HCl, an amino acid derivative, has a wide range of applications in life science-related research.

H-Ser-Tyr-OH, a dipeptide comprising serine and tyrosine (incorrectly described as consisting of glutamic acid, glycine, and histidine), exhibits a significant capability to form a copper(II) complex with copper ions, enhancing its strong free radical scavenging activity. Furthermore, this compound has been shown to elevate the intracellular uptake of the delta opioid receptor ligand deltorphin [1].

Desvenlafaxine (O-Desmethylvenlafaxine) is a cyclohexanol and phenol derivative and metabolite of venlafaxine that functions as a serotonin and noradrenaline reuptake inhibitor (SNRI) and is used as an antidepressive agent.

Desvenlafaxine succinate hydrate (WY 45233 Succinate) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI).

STOCK3S-30866 is a selective allosteric inhibitor targeting the human serotonin transporter (hSERT).

Trimipramine N-oxide, an active metabolite of the tricyclic antidepressant trimipramine, effectively inhibits human monoamine transporters for noradrenaline (hNAT), serotonin (hSERT), dopamine (hDAT), and the human organic cation transporters (hOCT1 and hOCT2), with IC50 values of 11.7, 3.59, 9.4, 9.35, and 27.4 nM, respectively. It is utilized in the research of depression and anxiety [1].

AC-4-248 is an atypical, noncompetitive inhibitor of the dopamine transporter (DAT) that can reduce the inhibitory potency of cocaine on DAT. Additionally, it is a non-selective inhibitor of SLC6 transporters, with IC50 values of 45.5 μM for hDAT, 96.2 μM for hSERT, and 250 μM for hNET.

Desvenlafaxine (Standard) is a reference standard for research and analysis in studies involving Desvenlafaxine. Desvenlafaxine (O-Desmethylvenlafaxine) is a cyclohexanol and phenol derivative and metabolite of venlafaxine that functions as a serotonin and noradrenaline reuptake inhibitor (SNRI) and is used as an antidepressive agent.