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Results for "
hirudin (5465; nonsulfated) (trifluoroacetate salt)
" in TargetMol Product Catalog- Inhibitors & Agonists1
Hirudin (54-65; non-sulfated) (trifluoroacetate salt)
T35583
Hirudin (54-65; non-sulfated) is a desulfated peptide fragment of hirudin, an anticoagulant produced byH. medicinalis.1It inhibits fibrin clot formation induced by isolated bovine thrombin with an IC50value of 3.7 μM.2 1.Niehrs, C., Huttner, W.B., Carvallo, D., et al.Conversion of recombinant hirudin to the natural form by in vitro tyrosine sulfation. Differential substrate specificities of leech and bovine tyrosylprotein sulfotransferasesJ. Biol. Chem.265(16)9314-9318(1990) 2.Payne, M.H., Krstenansky, J.L., Yates, M.T., et al.Positional effects of sulfation in hirudin and hirudin PA related anticoagulant peptidesJ. Med. Chem.34(3)1184-1187(1991)
- $133
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Hirudin (54-65; non-sulfated)
T126366113274-56-9
Hirudin is a thrombin inhibitor that improves Gsdmd-mediated pyroptosis by inhibiting irf2. It can be used in research on diabetic nephropathy.
- $189
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