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hif-2alpha agonist 2

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
HIF-2α agonist 2
T678312750141-15-0In house
HIF-2α agonist 2 is an HIF-2α agonist with an EC50 value of 1.68 μM for HIF-2α. HIF-2α agonist 2 can promote the stability of the ARNT A B ring in the 3z structure of HIF-2a-ARNT complex without cytotoxicity to 786-o-Reha-Luc cells. HIF-2α agonist 2 can be used in the study of oxygen metabolism and is closely related to the occurrence of cancer.
  • Inquiry Price
8-10weeks
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QTY
TargetMol | Inhibitor Sale
M1002
T61822823830-85-9In house
M1002 is a hypoxia-inducible factor-2 (HIF-2) agonist that enhances the affinity of HIF-2alpha and ARNT for transcriptional activation. It alters the Tyr2 conformation of the HIF-2alpha PAS-B structural domain and acts synergistically with inhibitors of the prolyl hydroxylase structural domain (PHD).
  • Inquiry Price
6-8 weeks
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