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(2)
By Target- Hedgehog/Smoothened
- Smo(1)
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Results for "
hh ag1.5
" in TargetMol Product Catalog- Inhibitors & Agonists2
Hh-Ag1.5
SAG-1.5, SAG1.5, SAG 1.5
T24754612542-14-0
Hh-Ag1.5 (SAG-1.5) is a potent Hedgehog (Hh) agonist (EC50: 1 nM) and Smoothened (Smo) receptor agonist, with an EC50 of 1 nM and Ki values between 0.5 and 2.3 nM for Smo. Hh-Ag1.5-mediated reprogramming breaks the quiescent state of non-injured hepatic stem cells and thus rescues liver failure. Hh-Ag1.5 induced differentiation of hiPSCs into skin precursor cells, spinal motor neurons and spinal sensory neurons.
- $129
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ALLO-2
T141881357350-60-7
ALLO-2 is a Inhibitor of Drug-Resistant Smo Mutant.It inhibits Smo agonist Hh-Ag1.5-induced luciferase expression in TM3-Gli-Luc cells with IC50 of 6 nM.
- $58
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