hexokinase

2-Deoxy-D-glucose (2-DG) is an analog of glucose, an inhibitor of glycolysis. 2-Deoxy-D-glucose has antiviral activity, as well as inhibitory cell proliferation and apoptosis-inducing activity.

D-mannoheptose is the main non-structural carbohydrate in avocado. D-mannoheptose is a specific inhibitor of D-glucose phosphorylation. D-mannoheptose can prevent the release of insulin and the utilization of carbohydrates in rats.

In cells, D-Glucose 6-phosphate sodium (G6P) is generated when glucose is phosphorylated by hexokinase or glucokinase or by the conversion of glucose-1-phosphate by phosphoglucomutase during glycogenolysis. G6P lies at the beginning of both glycolysis and the pentose phosphate pathways. It also can be stored as glycogen when blood glucose levels are high.

L-Glucose (L-(-)-Glucose), an enantiomer of D-glucose, is not bioavailable to cells as an energy source because it cannot be phosphorylated by hexokinase.

Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue.

Methyl 2-(3-oxo-2-(pent-2-en-1-yl)cyclopentyl)acetate ((±)-Jasmonic Acid methyl ester) induces the synthesis of proteinase inhibitors in plant leaves, suppresses proliferation, and induces apoptosis in cancer cells. It inhibits hexokinase bound to mitochondria, disrupting mitochondrial hexokinase activity to selectively target and kill cancer cells. Derivatives of Methyl 2-(3-oxo-2-(pent-2-en-1-yl)cyclopentyl)acetate also exhibit potential as anti-inflammatory agents, and the compound has been primarily detected in urine.

In cells, D-Glucose 6-phosphate potassium salt (G6P) is generated when glucose is phosphorylated by hexokinase or glucokinase or by the conversion of glucose-1-phosphate by phosphoglucomutase during glycogenolysis. G6P lies at the beginning of both glycolysis and the pentose phosphate pathways. It also can be stored as glycogen when blood glucose levels are high.