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(3)
By Target- Histone Demethylase
- Apoptosis(1)
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Results for "
h3k27me3/me2
" in TargetMol Product Catalog- Inhibitors & Agonists4
GSK-J4
Cited
GSK J4
T31001373423-53-0In house
GSK-J4 (GSK J4 HCl) is a cell permeable prodrug of GSK-J1, a dual inhibitor of the H3K27me3 me2 demethylases JMJD3 KDM6B and UTX KDM6A (IC50=8.6 6.6 μM). GSK-J4 induces endoplasmic reticulum stress-related apoptosis.
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CitedGSK-J4 Hydrochloride
GSK J4 HCl (1373423-53-0 free base), GSK J4 HCl
T43831797983-09-5
GSK-J4 Hydrochloride (GSK J4 HCl) is a cell permeable, potent and selective histone demethylase(JMJD3 )inhibitor. is an ethyl ester derivative of the GSK-J1 with an IC50 value greater than 50 μM in vitro.
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GSK-J2 sodium
T865292108665-15-0
GSK-J2 sodium, the sodium form of GSK-J2, is an isomer of GSK-J1 and lacks specific activity. GSK-J1 is a potent inhibitor of H3K27me3 me2-demethylases JMJD3 KDM6B and UTX KDM6A [1].
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GSK-J1 lithium salt
T114752309668-29-7
GSK-J1 lithium salt is an effective inhibitor of H3K27me3 me2-demethylases JMJD3 KDM6B and UTX KDM6A, with an IC 50 of 60 nM for KDM6B.
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