h-gly-gly-pro-oh

H-Gly-Gly-Pro-OH (Glycyl-glycyl-L-proline) is a dipeptide composed of glycine and proline, and is an end product of collagen metabolism that is further cleaved by prolidase.

H-Gly-Arg-Gly-Asp-Asn-Pro-OH (GRGDNP) is a integrin-ligand interactions inhibitor.

H-Gly-Pro-OH (Glycyl proline) is a dipeptide composed of glycine and proline, and is an end product of collagen metabolism

H-Gly-Pro-Hyp-OH is a potent and orally available anti-photoaging collagen peptide that attenuates inflammation and reduces MMP-1 and MMP-3 levels; attenuates H2O2-induced aging of dermal fibroblasts; restores cortisol-mediated inhibition of type I collagen and GR activation and (TGF)-β signaling signaling, among other things; and improves the hydration of human skin, elasticity and anti-wrinkle properties.

H-Pro-Gly-Pro-OH, a collagen-derived matrikine, traditionally acts as a neutrophil chemoattractant, guiding these cells to target locations to orchestrate localized repair responses. Additionally, this compound initiates the transcription of neurotrophins and their receptor genes following cerebral ischemia [1] [2].

[Leu144,Arg147]-PLP (139-151) is a mutated fragment of the myelin proteolipid protein (PLP), featuring substitutions of tryptophan to leucine and histidine to arginine at positions 144 and 147, respectively. Immunizing mice with this peptide (50 µg) mixed in complete Freund's adjuvant (CFA) elevates IL-4 levels in the spleen. While it suppresses Th1 cell activation in vitro, it does not do so in vivo; instead, it promotes the development of regulatory T cells. Preimmunization with [Leu144, Arg147]-PLP (139-151) postpones the onset of experimental autoimmune encephalomyelitis (EAE) triggered by encephalitogenic peptides from PLP (178-191), myelin oligodendrocyte glycoprotein (MOG) (92-106), or myelin basic protein (MBP) in mice.