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gtp-loaded

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  • Inhibitors & Agonists
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    TargetMol | All_Pathways
  • PROTAC Products
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    TargetMol | PROTAC
BI-3406
T129792230836-55-0
BI-3406 is an orally active, highly potent and selective between KRAS and Son of Sevenless 1 (SOS1) interaction inhibitor(IC50 : 6 nM),with anticancer activity.
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TargetMol | Citations Cited
ACBI-4
T212494
ACBI-4 is a selective PROTAC degrader targeting the active state of GTP-loaded KRAS (KRAS(on)). It demonstrates significant antiproliferative effects and effectively degrades various KRAS mutants in cancer cells, such as KRASG12R.
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