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(3)
By Target- Ras
- PROTACs(2)
- Kras(1)
- Raf(1)
- p38 MAPK(1)
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By Target By ResearchField- Cancer(1)
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Results for "
gtp-loaded
" in TargetMol Product Catalog.- Inhibitors & Agonists3
- PROTAC Products2
Cited(R)-ACBI-4
T2161933097973-97-9
(R)-ACBI-4 is an isomer of ACBI-4. ACBI-4 acts as a selective PROTAC degrader targeting the GTP-loaded active state of KRAS (KRAS(on)). It exhibits significant antiproliferative effects and effectively degrades various KRAS mutants, such as KRASG12R, in cancer cells.
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