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(1)
By Target- Histone Demethylase
- Monoamine Oxidase(1)
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By Target By ResearchField- Cancer(1)
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Results for "
gsk-lsd-1 dihydrochloride
" in TargetMol Product Catalog.- Inhibitors & Agonists1
GSK-LSD1 dihydrochloride
Cited
GSK-LSD1 2HCl, GSK-LSD1 (hydrochloride)
T23152102933-95-7
GSK-LSD1 dihydrochloride (GSK-LSD1 2HCl) is a highly potent, specific, and irreversible LSD1 inhibitor (IC50 = 16 nM). By inhibiting LSD1-mediated epigenetic modifications, GSK-LSD1 dihydrochloride promotes differentiation and inhibits proliferation in cancer cells, demonstrating antitumor activity in various hematologic malignancies and certain solid tumor models. GSK-LSD1 dihydrochloride can be used in research in the fields of epigenetics, oncology, metabolism, and inflammation.
- $34
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QTY
Cited
T822541431368-48-7
GSK-LSD1 is a selective LSD1 inhibitor with potential anticancer activity that attenuates the expression of CTGF/CCN2, MMP13, LOXL4, and waveform proteins in cancer cells.GSK-LSD1 regulates the cell cycle, induces apoptosis, and can be used to study breast cancer.
- $30
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