gsk 126

GSK126 (GSK2816126A) is a excellently specific EZH2 methyltransferase inhibitor ( IC50=9.9 nM).

GSK-1268997 is a PRMT5 inhibitor and can be used to study advanced solid tumors.

Cabotegravir (S/GSK1265744) (GSK744, GSK1265744) is a long-acting HIV integrase inhibitor and inhibits the HIV-1 integrase catalyzed strand transfer reaction (IC50: 3.0 nM).

GSK-1268992 is a bio-active chemical.

Cabotegravir sodium (GSK-1265744) is an orally active, membrane-permeable HIV integrase inhibitor (IC₅₀ = 2.5 μM) and also an OAT1/OAT3 inhibitor (IC₅₀ = 0.81/0.41 μM). It inhibits HIV replication and may be used in AIDS research.

VPC03090 is a Sphingosine-1-Phosphate Receptor Inhibitor. VPC03090 is an analog of FTY-720, acts as antagonist for S1PR1 and S1PR3. VPC03090-P, converted from VPC03090 through the phosphorylation by SK-2, causes a reduction in tumor growth in mice with mammary cancer, and its oral bioavailability is determined to be 30 hours.

GSK-1264 is an allosteric inhibitor of human immunodeficiency virus (HIV) integrase which blocks viral replication and abnormal multimerization involving specific protein domains.