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By Target- Potassium Channel
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Results for "
girk1/2
" in TargetMol Product Catalog- Inhibitors & Agonists3
VU0529331
T172461286725-49-2
VU0529331 is a modestly selective non-GIRK1-containing G protein-gated, inwardly-rectifying, potassium channel activator (EC50s: 5.1 μM and 5.2 μM for GIRK2 and GIRK1 2 in HEK293 cells, respectively), and is also effective on the GIRK4 homomeric channel.
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ML 297
ML297
T46641443246-62-5
ML 297 is a selective Kir3.1 3.2 (GIRK1 2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1 2, GIRK1 4 and GIRK1 3 respectively). ML 297 exhibits no effect on GIRK2, GIRK2 3, Kir2.1 and Kv7.4 channels, and has minimal effect on a panel of other ion channels, receptors and transporters.
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