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Results for "
gdc2394
" in TargetMol Product Catalog- Inhibitors & Agonists2
GDC-2394
T697452238822-07-4
GDC-2394, an orally active, selective NLRP3 inhibitor, also targets IL-1β, exhibiting inhibitory concentrations (IC50s) of 0.4 μM (human IL-1β) and 0.1 μM (mouse IL-1β). It effectively hampers NLRP3-induced caspase-1 activity while not affecting NLRC4-dependent inflammasome activation.
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