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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5421 | KDU691 | Parasite , PI4K | |
KDU691 is a PI4K inhibitor. | |||
T39256 | MMV674850 | MMV674850 | |
MMV674850 exhibits potency against asexual stage parasites, with IC50 values of 2.7 and 4.5 nM. Furthermore, it demonstrates a preferential affinity for early-stage gametocytes, displaying an IC50 value of 4.5 ± 3.6 nM, ... | |||
T79460 | Antimalarial agent 28 | Parasite | |
Antimalarial agent 28 (Compound 2i) acts as an antiplasmodial agent, exhibiting inhibition of P. berghei with IC50 values of 0.561 μM for the liver stage, 0.14 μM for early gametocytes, and 4.34 μM for the ring stages of... | |||
T9763 | MMV666810 | ||
MMV666810, a 2-aminopyrazine analogue of MMV390048, exhibits potent antiplasmodial activity against asexual parasites with an IC50 value of 5.94 nM. It demonstrates enhanced efficacy against late-stage gametocytes with a... | |||
T61572 | FNDR-20123 free base | ||
FNDR-20123 free base, a pioneering and orally administered anti-malarial agent, acts as a Histone Deacetylase (HDAC) inhibitor, displaying potent efficacy with IC50 values of 31 nM for Plasmodium and 3 nM for human HDAC,... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T75450 | P-orlandin | ||
P-orlandin, a fungal metabolite, effectively impedes Plasmodium falciparum infection in mosquitoes by preventing FREP1 from binding to gametocytes or ookinetes [1]. |