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Search Results for " gametocytes "

Targets

5

Compounds

1

Natural Products

Cat No. Product Name Synonyms Targets
T5421 KDU691 Parasite , PI4K
KDU691 is a PI4K inhibitor.
T39256 MMV674850 MMV674850
MMV674850 exhibits potency against asexual stage parasites, with IC50 values of 2.7 and 4.5 nM. Furthermore, it demonstrates a preferential affinity for early-stage gametocytes, displaying an IC50 value of 4.5 ± 3.6 nM, ...
T79460 Antimalarial agent 28 Parasite
Antimalarial agent 28 (Compound 2i) acts as an antiplasmodial agent, exhibiting inhibition of P. berghei with IC50 values of 0.561 μM for the liver stage, 0.14 μM for early gametocytes, and 4.34 μM for the ring stages of...
T9763 MMV666810
MMV666810, a 2-aminopyrazine analogue of MMV390048, exhibits potent antiplasmodial activity against asexual parasites with an IC50 value of 5.94 nM. It demonstrates enhanced efficacy against late-stage gametocytes with a...
T61572 FNDR-20123 free base
FNDR-20123 free base, a pioneering and orally administered anti-malarial agent, acts as a Histone Deacetylase (HDAC) inhibitor, displaying potent efficacy with IC50 values of 31 nM for Plasmodium and 3 nM for human HDAC,...
Cat No. Product Name Synonyms Targets
T75450 P-orlandin
P-orlandin, a fungal metabolite, effectively impedes Plasmodium falciparum infection in mosquitoes by preventing FREP1 from binding to gametocytes or ookinetes [1].
TargetMol