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By Target- Liver X Receptor
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By Target By ResearchField- Cancer(2)
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Results for "
gac0003a4
" in TargetMol Product Catalog- Inhibitors & Agonists2
GAC0001E5
T68323927969-67-3
GAC0001E5 (1E5) is a dual LXR inverse agonist and degrader (IC50 = 5.4-9.1 μM in pancreatic cancer cells). It inhibits tumor growth and induces apoptosis by promoting LXRα/β degradation and suppressing transcriptional activity.
- $970
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QTY
GAC0003A4
GAC0001E5
T68316929492-71-7
GAC0003A4 is a potent LXR inverse agonist with antitumor activity that inhibits the transcription of LXR proteins.GAC0003A4 degrades LXRβ proteins and inhibits the proliferation of PDAC cells in a dose-dependent manner.GAC0003A4 has been used in the study of advanced pancreatic cancers and other recalcitrant malignancies.
- $67
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