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By Target- AMPK
- IκB/IKK(1)
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Results for "
fortunellin
" in TargetMol Product Catalog- Inhibitors & Agonists1
- Natural Products1
Fortunellin
TN407720633-93-6
Fortunellin is a flavonoid isolated from Fortunella margarita (kumquat) that alleviates histopathological heart injury while improving cardiac function by reducing inflammation and oxidative stress in fructose-induced metabolic disease models. Fortunellin decreases pro-inflammatory cytokines and suppresses phosphorylation of IKKα, IκBα, and NF-κB, while upregulating antioxidant defenses including SOD, CAT, HO-1, and activating AMPK/Nrf2 signaling, supporting the use of Fortunellin in research on diabetic cardiomyopathy and cardiometabolic disorders.
- $44
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