fe2+

PHD-1-IN-1 is a potent inhibitor of hypoxia-inducible factor prolylhydroxylase domain-1 (PHD-1) enzyme(IC50 = 0.034 μM).

1. Thonningianin A has anti-cancer activities.2. Thonningianin A represents a new potent glutathione S-transferase in vitro inhibitor.3. Thonningianin A has antioxidant property, involves radical scavenging, anti-superoxide formation and metal chelation.

6-epiforesticine is an alkaloid discovered in Aconitum handelianum that exhibits chelating activity toward ferrous ions (Fe²⁺) (IC₅₀ = 5.04 mg/L) and possesses potential antioxidant effects.

Degarelix is a peptide and selective GnRH (human gonadotropin-releasing hormone) receptor antagonist that treats prostate cancer by lowering testosterone levels in the body.

Merotocin is a potent and highly selective peptidic agonist of the oxytocin receptor.

Selepressin, an analog of vasopressin, is a potent, selective vasopressin V1a receptor agonist.

Barusiban is an oxytocin receptor antagonist.

RK-52 is a synthetic inhibitor of rhodesain, characterized by an impressive ksecond value (ksecond = 67000 × 103 M−1 min−1) and by a picomolar affinity toward the trypanosomal protease (Ki = 38 pM).

FE-200041 is a peripheral efficacious kappa opioid agonist.

GR-127935 is a potent and selective 5-HT1B/1D receptor antagonist.

CR 665 (JNJ 38488502) is a peripherally selective κ-opioid agonist with an EC50 of 10.9 nM for kappa opioid receptor activation, used in peripheral pain research.

DISC-0974 is a humanized antibody that targets RGMC/HFE2. By blocking the BMP/HJV signaling pathway, DISC-0974 inhibits ferritin expression and promotes iron absorption and utilization. DISC-0974 can be used in research on anemia.

11(Z),14(Z),17(Z)-Eicosatrienoic acid methyl ester is the ester derivative of 11(Z),14(Z),17(Z)-eicosatrienoic acid, identified within lipid-producing microalgae Nannochloropsis, as well as in diesel-contaminated soils and residential wastewater.

Sterculic acid methyl ester, an ester derivative of sterculic acid known for inhibiting Δ9 desaturase, has been found to adversely affect and exhibit toxicity towards R. opacus bacteria at a concentration of 0.75 mM. It not only hampers bacterial growth but also modifies fatty acid composition by reducing stearate and oleate levels, increasing the palmitate ratio, and decreasing overall fatty acid content at 0.25 or 0.5 mM concentrations. Additionally, at 50 ppm, Sterculic acid methyl ester enhances the tumor growth-promoting effects of aflatoxin Q1 in rainbow trout, indicating a synergistic interaction between the two compounds. [Matreya, LLC. Catalog No. 1236]

All-cis-4,7,10,13,16-Docosapentaenoic acid ethyl ester (all-cis-4,7,10,13,16-DPA ethyl ester) is a derivative of docosapentaenoic acid (DPA), an omega-3 fatty acid prevalent in fish oils. This ethyl ester form is commonly included in dietary supplements formulations to enhance omega-3 fatty acid intake.

Cis-10-Nonadecenoic acid methyl ester, a fatty acid methyl ester, serves as a chromatography standard for the quantification of cis-nonadecenoic acid.

17-Methyl stearic acid methyl ester is a methylated derivative of fatty acid methyl ester, identified in mutton tallow and as a volatile constituent in roasted tigernut (C. esculentus) oil [Matreya, LLC. Catalog No. 1603].

Ethyl Tricosanoate, a long-chain saturated fatty acid ethyl ester, is found in small amounts in C. conicum and C. conicum. The free acid form reduces the hemolytic activity of Staphylococcus aureus delta toxin on human erythrocytes.

Phytanic acid methyl ester is an esterified form of long-chain fatty acids and specifically phytanic acid, identified in Greek tobacco.

Apraglutide TFA (FE 203799 TFA), a synthetic 33-amino-acid peptide and a long-acting GLP-2 analogue, enhances adaptation and linear intestinal growth in a neonatal piglet model of short bowel syndrome with total resection of the ileum.

Apraglutide (FE 203799 is a synthetic 33-amino acid peptide and long-acting glp-2 analogue.

Nitroxoline (5-nitroquinolin-8-ol) is a urinary antibacterial agent active against susceptible gram-positive and gram-negative organisms commonly found in urinary tract infections.

o-Phenanthroline (1,10-Phenanthroline) , a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells.o-Phenanthroline protects mammalian cells from hydrogen peroxide-induced gene mutation and morphological transformation.

o-Phenanthroline monohydrate (1, 10-Phenanthroline monohydrate) is an inhibitor of metallopeptidases, inhibits zinc-dependent hydrolysis of Fa-Gly-Leu-NH2 by B. subtilis neutral protease and B. thermoproteolyticus thermolysin.