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By Target- Apoptosis
- DNA/RNA Synthesis(1)
- Topoisomerase(1)
- Others(2)
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Results for "
epirubicin
" in TargetMol Product Catalog- Inhibitors & Agonists3
Epirubicin
IMI-28, IMI 28, epi DX, 4-epidoxorubicin, 4'-Epidoxorubicin, 4-epiadriamycin, 4-epi DX
T6909356420-45-2
Epirubicin (4'-Epidoxorubicin), a semisynthetic L-arabino derivative of doxorubicin, acts as an antineoplastic agent by inhibiting Topoisomerase, thus impeding DNA and RNA synthesis. Additionally, it functions as a Forkhead box protein p3 (Foxp3) inhibitor, curbing regulatory T cell activity.
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Epirubicin hydrochloride
Cited
Pharmorubicin, Epirubicin HCl, 4'-Epidoxorubicin hydrochloride, 4'-epidoxorubicin HCl
T012556390-09-1
Epirubicin hydrochloride (Pharmorubicin) is an adriamycin derivative, a topoisomerase (Topo) inhibitor, and a Forkhead box protein p3 (Foxp3) inhibitor. Epirubicin hydrochloride has antitumor activity.
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Citednr-160
T370682484895-50-1
NR-160 is an inhibitor of histone deacetylase 6 (HDAC6; IC50= 0.03 μM).1It is selective for HDAC6 over HDAC1, -2, -3, -4, and -8 (IC50s = 5.18, 2.26, 8.48, 55.4, and 14.7 μM, respectively). NR-160 is cytotoxic against a panel of seven cancer cell lines (IC50s = 22.5-51.8 μM). It enhances cytotoxicity induced by bortezomib in HL-60 cells, as well as cytotoxicity induced by epirubicin or daunorubicin in CCRF-HSB-2 T cell acute lymphoblastic leukemia cells.
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