enzyme

GSK1940029 (SCD inhibitor 1) is an inhibitor of stearoyl-CoA desaturase (SCD).

Amylase (Diastase) is any one of a group of enzymes which catalyses the breakdown of starch into maltose.

(Rac)-Telmesteine (3,4-Thiazolidinedicarboxylic Acid 3-Ethyl Ester) is an inhibitor of protease and is thus a suitable enzyme stabilizer.

L-Dihydroorotic acid, also known as (S)-4,5-dihydroorotate or dihydro-L-orotate, belongs to the class of organic compounds known as alpha amino acids and derivatives. Within the cell, L-dihydroorotic acid is primarily located in the cytoplasm and mitochon

Temocapril is an inhibitor of tyrosine kinase.

Alkaline Phosphatase is a nonspecific phosphomonoesterase that catalyzes the hydrolysis of phosphomonoesters under alkaline conditions and also catalyzes the transfer of phosphate groups. It can be used in clinical testing, enzyme-linked immunosorbent assays, and other experiments.

TH1085 is an enhancer of OGG1. TH1085 stimulates DNA repair and protects cells from the environmental hazard paraquat (PQ).

NAE-IN-M22 (NEDD8 inhibitor M22) is a selective, potent and reversible inhibitor of NEDD8 activating enzyme (NAE). NAE-IN-M22 inhibits multiple cancer cell lines and induces apoptosis in A549 cells. NAE-IN-M22 also can inhibit tumor growth in vivo.

UUN44923 is a FTO inhibitor. It may be useful for treating diseases assocd. with FTO targets, obesity, metabolic syndrome (MS) , type 2 diabetes (T2D) , Alzheimer's diseases, breast cancers, small- cell lung cancers, a human bone marrow striated muscle cancer, a pancreatic cancer, malignant glioblastoma and the like.

Enzyme-IN-3 disodium (compound 7) is a selective inhibitor of Mycobacterium tuberculosis shikimate kinase with an IC50 of 1.6 μM. Additionally, Enzyme-IN-3 disodium exhibits antibacterial properties.

Enzyme-IN-1 (compound 1), a peptide-based inhibitor of N-terminal nucleophile (Ntn) hydrolases, specifically targets and inhibits the chymotrypsin-like activity (CT-L) of the 20S proteasome. This compound may possess potential anti-inflammatory properties [1].

Enzyme-IN-2 (compound 15) is a potent urease inhibitor, demonstrating anti-ureolytic activity with a K_i of 2.36 µM and an IC_50 of 0.75 µM [1].

HumanCES2Enzyme is a recombinant CES2 enzyme that hydrolyzes carboxylic ester bonds, thioester bonds, and amide bonds in numerous exogenous and endogenous compounds (including lipids).

HumanCES1Enzyme is a recombinant CES1 enzyme responsible for hydrolyzing ester- and amide-containing molecules. Predominantly expressed in the liver, it plays a crucial role in processing active metabolites and participates in ester exchange reactions.

Ubiquitin Conjugating Enzyme E2C (EC 2.3.2.24) is a member of the E2 ubiquitin-conjugating enzyme family and serves as a key regulatory factor in the protein degradation pathway in eukaryotes. It is involved in the development and progression of various malignant tumors and plays a role in the degradation of mitotic cycle proteins, thereby impacting cell cycle progression. Additionally, Ubiquitin Conjugating Enzyme E2C acts as a prognostic marker for cholangiocarcinoma.

Cellular digestive enzyme is commonly used as an alternative to trypsin for detaching adherent cells from culture dishes.

Angiotensin Converting Enzyme, Rabbit (EC 3.4.15.1), indirectly elevates blood pressure by causing vasoconstriction. This enzyme achieves its effect by converting angiotensin I into angiotensin II, with the latter having the ability to constrict blood vessels.

Angiotensin Converting Enzyme, Rat (EC 3.4.15.1), indirectly raises blood pressure by causing blood vessel constriction. It achieves this effect by converting angiotensin I into angiotensin II, which has the property of constricting blood vessels.

C1sEnzyme is a subunit of the complement C1 complex, functioning as a serine protease to activate the complement system. It can cleave LRP5 and LRP6, thereby activating the Wnt/β-Catenin signaling pathway. Additionally, C1sEnzyme promotes macrophage M2 polarization while inhibiting M1 polarization and enhances exocytosis, exhibiting anti-inflammatory properties.

Malic enzyme inhibitor ME1 (ME1) is a specific inhibitor of Malic enzyme (IC50 = 0.15 μM). Malic enzyme inhibitor ME1 reduces cell viability/metabolic activity.

Angiotensin-converting enzyme (Kininase II) is a zinc-dependent peptidase and extracellular enzyme that acts as a counterbalance to ACE in the renin-angiotensin system.Angiotensin-converting enzyme is a potent vasoconstrictor used in the study of cardiovascular and immune diseases. Angiotensin-converting enzyme is a potent vasoconstrictor used to study cardiovascular and immune diseases.

Vaccinia virus capping enzyme is a transcription initiation factor that functions as a heterodimer composed of D1 (844 aa) and D12 (287 aa) polypeptides, capable of performing all three steps of m7GpppRNA synthesis. It has been widely utilized as a reagent for in vitro capping and for labeling capped RNA.

Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycetes, functioning as an XBP1 inhibitor and inhibiting IRE1α-induced ATP-dependent XBP1 mRNA cleavage (IC50: 80 nM), and induces apoptosis.

Pevonedistat (MLN4924) is a potent and selective NEDD8 activating enzyme (NAE) inhibitor (IC50=4.7 nM) with therapeutic potential for myelodysplastic syndromes (MDS) and antitumor activity.