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Results for "
emapalumab
" in TargetMol Product Catalog- Inhibitors & Agonists1
- Inhibitory Antibodies1
Emapalumab
NI-0501
T767421709815-23-5
Emapalumab (NI-0501) is an IgG1 monoclonal antibody that humanizes human monoclonal antibodies against interferon gamma, blocking its binding to cell surface receptors and activating inflammatory signaling. Emapalumab has a high binding force (Kd=1.4 pM) to free IFN-γ and to IFN-γ bound to its receptor. Emapalumab can be used in the study of hemophagocytic lymphohistiocytosis (HLH).
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