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(3)
By Target- EGFR
- Apoptosis(2)
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Results for "
egfr (exon 19del)
" in TargetMol Product Catalog- Inhibitors & Agonists3
Mutated EGFR-IN-1
Osimertinib analog
T161621421372-66-8
Mutated EGFR-IN-1 (Osimertinib analog) is a valuable intermediate in designing inhibitors for mutated EGFR, including L858R EGFR, Exon19 deletion activating mutant, and T790M resistance mutant.
- $53
Size
QTY
AZD3759 hydrochloride
T42491626387-81-2
AZD3759 (hydrochloride) is an effective, orally active and central nervous system-penetrant EGFR inhibitor. At Km ATP concentrations, the IC50s are 0.2/0.3/0.2 nM for EGFR (L858R)/EGFR (wt)/EGFR (exon 19Del).
- $30
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QTY
Zorifertinib
AZD3759
T36591626387-80-1
Zorifertinib (AZD3759) is an orally active, effective and central nervous system-penetrant EGFR inhibitor. The IC50 values were 0.2, 0.3 and 0.2 nM for EGFR L858R mutant, TK wild-type, and Exon 19Del enzymes, respectively.
- $37
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QTY
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