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egfr (exon 19de)

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  • Inhibitors & Agonists
    2
    TargetMol | All_Pathways
Mutated EGFR-IN-1
Osimertinib analog
T161621421372-66-8
Mutated EGFR-IN-1 (Osimertinib analog) is a valuable intermediate in designing inhibitors for mutated EGFR, including L858R EGFR, Exon19 deletion activating mutant, and T790M resistance mutant.
  • $53
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AZD3759 hydrochloride
T42491626387-81-2
AZD3759 (hydrochloride) is an effective, orally active and central nervous system-penetrant EGFR inhibitor. At Km ATP concentrations, the IC50s are 0.2/0.3/0.2 nM for EGFR (L858R)/EGFR (wt)/EGFR (exon 19Del).
  • $30
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