ec 18.

EC18 is a bioactive chemical.

AZ3971 is a potent BACE1 inhibitor. AZ3971 blocks BACE1-mediated cleavage of APP and inhibits Aβ42 production HEK cells overexpressing the APP protein which carries the Swedish mutation (HEK.APPswe).

L-threo-Sphingosine C-18 is a protein kinase C inhibitor.

2,2,3,3-Tetramethyl-4,7,10,13,16-pentaoxa-3-silanonadec-18-yne is a useful organic compound for research related to life sciences and the catalog number is T64752.

18:0-LPS (Lysophosphatidylserine C18:0) is an endogenous lipid identified during the oxidation of phospholipids. It holds potential for use in cardiovascular disease research.

EIPA (L593754) is a TRPP3 channel inhibitor (IC50=10.5 μM) and an inhibitor of Na+/H+ exchange (NHE). EIPA inhibits megacytosis, promotes autophagy, and can be used in inflammation and tumor studies.

Lansoprazole sulfide (AG-177) is an active metabolite of Lansoprazole with similar activity.Lansoprazole is a proton pump inhibitor and antitubercular agent with an IC50= 0.59 µM against Mycobacterium tuberculosis.

S1P1 Agonist III is an effective, orally active S1P1 receptor agonist with an EC₅₀ of 18 nM, S1P1 Agonist III has potential application in research related in inflammation and immunology.

eIF4A3-IN-18, a silvestrol analogue, disrupts the formation of the eIF4F translation complex, exhibiting EC 50 values of 0.8, 35, and 2 nM for myc-LUC, tub-LUC, and the growth inhibition of MBA-MB-231 cells, respectively. Additionally, it demonstrates cytotoxicity towards RMPI-8226 cells with an LC 50 of 0.06 nM. This compound is utilized in researching human cancer pathogenesis [1].

Antiparasitic agent-18 (compound 3a) exhibits potent and selective antiprotozoal activity, effectively inhibiting T. brucei (EC50 = 0.4 µM), T. cruzi (EC50 = 0.21 µM), and L. donovani (EC50 = 0.26 µM) [1].

Lanopylin A2 inhibits recombinant human lanosterol synthase (human lanosterol synthase) [EC 5.4.99.7] with an IC50 of 18 μM.