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By Target- Histamine Receptor
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Results for "
ebastine
" in TargetMol Product Catalog- Inhibitors & Agonists3
Ebastine
Ebastel, LAS-W 090, Ebastin, Kestine, RP64305
T233590729-43-4
Ebastine (Kestine) (trade names Evastin, Kestine, Ebastel, Aleva) is a non-sedating H1 antihistamine. It does not penetrate the blood-brain barrier and thus allows an effective block of the H1 receptor in peripheral tissue without a central side effect, i. e not causing sedation or drowsiness.
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Hydroxy Ebastine
T37515210686-41-2
Hydroxy Ebastine is an ebastine metabolite. Ebastine undergoes rapid first-pass metabolism by the cytochrome P450 isoform CYP2J2 to form hydroxy ebastine which is then metabolized by CYP2J2 and CYP3A4 to form carebastine.
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Carebastine 
T1068090729-42-3
Carebastine, the active metabolite of Ebastine, is an antagonist of the histamine H1 receptor.
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