dppe

DPPE-mPEG, a PEG-modified lipid, minimizes nonspecific protein adsorption and extends circulation time in vivo [1].

DPPE-MPEG(2000) is a polyethylene glycol (PEG) derivative of 1,2-dipalmitoyl-rac-glycero-3-phosphoethanolamine (DPPE), characterized as a PEGylated phospholipid.

DPPE-PEG2000 (16:0 PEG2000 PE) is a PEG-modified lipid known for reducing nonspecific protein adsorption and extending circulation time in vivo.

DPPE-PEG550 serves as a PEG lipid functional terminal group used for synthesizing liposomes (LPs) to design conjugated polymer nanoparticles. Liposome nanoparticles (LNPs) are capable of further coupling with other biomolecules through biotin modification and carboxyl terminals. Functionalized nanoparticles can target specific cell proteins for labeling purposes. Using streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles can bind with biotinylated antibodies on cell surface receptors, enabling applications in fluorescence-based imaging and sensing.

DPPE-PEG750 is a PEG lipid functional end group used for synthesizing liposomes (LPs) and designing conjugated polymer nanoparticles. Liposome nanoparticles (LNPs) modified with biotin and carboxylic ends can couple with other biomolecules. These functionalized nanoparticles are useful for targeting specific cell proteins. Using streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles can bind to biotinylated antibodies on cell surface receptors, facilitating fluorescence-based imaging and sensing applications.

DPPE-PEG1000 is a PEG lipid functional end group used for synthesizing liposomes (LPs) and is instrumental in designing conjugated polymer nanoparticles. Liposome nanoparticles (LNPs), featuring biotin modification and carboxyl terminals, can further couple with other biomolecules. These functionalized nanoparticles are useful for the targeted labeling of specific cell proteins. By employing streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles can bind to biotinylated antibodies on cell surface receptors, enabling applications in fluorescence-based imaging and sensing.

DPPE-PEG3000 is a PEG lipid functional end group used for synthesizing liposomes (LPs) and designing conjugated polymer nanoparticles. Liposome nanoparticles (LNPs) modified with biotin and having a carboxylate end can further couple with other biomolecules. The functionalized nanoparticles are applicable for targeted labeling of specific cell proteins. Using streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles can interact with biotinylated antibodies on cell surface receptors, facilitating fluorescence-based imaging and sensing applications.

DPPE-PEG5000 is a PEG lipid functional terminal group utilized for synthesizing liposomes (LPs) and designing conjugated polymer nanoparticles. Liposome nanoparticles (LNPs) with biotin modification and carboxyl ends can further couple with other biomolecules. These functionalized nanoparticles target specific cellular proteins for labeling. Using streptavidin as a linker, the biotinylated PEG lipid-conjugated polymer nanoparticles can bind to biotinylated antibodies on cell surface receptors, enabling applications in fluorescence-based imaging and sensing.

DPPE-PEG-amine (MW 2000) is a type of phospholipid. Phospholipids possess excellent biocompatibility and distinct amphiphilic properties, making them suitable and prominent excipients or formulations in drug delivery for enhancing therapeutic outcomes. DPPE-PEG-amine (MW 2000) is applicable in studies related to drug delivery.

m-PEG-DPPE (MW 2000) is a PEG lipid that enhances the delivery efficiency and tissue specificity of poorly soluble drugs. It is applicable for research in drug delivery studies.

DPPE-PEG350 is a PEG lipid-functional end group utilized in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. These liposome nanoparticles (LNPs) feature biotin modifications and carboxyl end groups, allowing further coupling with other biomolecules. Functionalized nanoparticles are employed for targeted labeling of specific cellular proteins. Using streptavidin as a linker, biotinylated PEG-lipid-conjugated polymer nanoparticles can bind to biotinylated antibodies on cell surface receptors, enabling applications in fluorescence-based imaging and sensing.

Tesmilifene fumarate (DPPE fumarate) (DPPE fumarate) is an H1C receptor antagonist.

1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) is a biotinylated phospholipid. It has been used in PEGylated polyamidoamine-dendrimer-conjugated supported lipid bilayers (SLB) to isolate circulating tumor cells and tumor cell microembolis from patient-derived blood by antibody-coated microfluidics. [1] It has also been used as a component of SLBs to detect protein-ligand binding with ortho-conjugated Texas Red DHPE. [2] In addition, 1,2-dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) has been used in SLBs partitioned into nanowells to create DNA curtains, which can be used as a high-throughput tool for detection of protein-DNA interactions at the single molecule level.[3]

1,2-Dipalmitoyl-13C-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycero-3-PC by GC- or LC-MS. 1,2-Dipalmitoyl-sn-glycero-3-PC (DPPC) is a zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers, bilayers, and liposomes for use in a variety of applications.1,2,3,4 It has been used in the formation of proteoliposomes for implantation of γ-glutamyl transpeptidase into human erythrocyte membranes.3 Incorporation of glycosphingolipid antigens into DPPC-containing liposomes increases the immunogenicity of the antigens in mice.4 |1. Ege, C., and Lee, K.Y.C. Insertion of Alzheimer's Aβ40 peptide into lipid monolayers. Biophys. J. 87(3), 1732-1740 (2004).|2. Leekumjorn, S., and Sum, A.K. Molecular simulation study of structural and dynamic properties of mixed DPPC/DPPE bilayers. Biophys. J. 90(11), 3951-3965 (2006).|3. Kalra, V.K., Sikka, S.C., and Sethi, G.S. Transport of amino acids in γ-glutamyl transpeptidase-implanted human erythrocytes. J. Biol. Chem. 256(11), 5567-5571 (1981).|4. Uemura, A., Watarai, S., Iwasaki, T., et al. Induction of immune responses against glycosphingolipid antigens: Comparison of antibody responses in mice immunized with antigen associated with liposomes prepared from various phospholipids. J. Vet. Med. Sci. 67(12), 1197-1201 (2005).

1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine (DPPE), a phospholipid member of the glycerophosphonoethanolamine family, is a major component in biological membranes. Studies have shown that cholesterol induces condensation of DPPE monolayers in the presence of Ca2+ ions, leading to more ordered lipid tails and resulting in a thicker membrane.

1,3-Dipalmitoyl glycero-2-phosphatidylethanolamine is a phospholipid incorporating saturated long-chain (16:0) stearic acid at the sn-1 and sn-3 positions, with phosphatidylethanolamine (PE) at the sn-2 position. Phosphatidylethanolamines, critical components of biological membranes, play essential structural and functional roles. Various PE types are instrumental in forming micelles, liposomes, and other synthetic membranes.

1-Palmitoyl-d9-2-palmitoyl-sn-glycero-3-PE serves as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycero-3-PE (1,2-DPPE) using GC- or LC-MS. 1,2-DPPE, a prevalent PE (phospholipid), contains C16:0 fatty acids at the sn-1 and sn-2 positions and is essential in the inner plasma membrane leaflet. This compound forms a condensed lipid monolayer with cholesterol through tight hydrogen bonding between 1,2-DPPE headgroups, enhancing membrane fluidity to support transport and signaling.

1,2-Dipalmitoyl-sn-glycero-3-N,N-dimethyl-PE is a derivative of 1,2-dipalmitoyl-sn-glycero-3-PE (1,2-DPPE) with two added methyl groups on its sn-3 moiety, which in aqueous suspensions, reduces the phase transition temperature relative to those of 1,2-DPPE and 1,2-dipalmitoyl-sn-glycero-3-N-methyl-PE (1,2-NMeDPPE). It is utilized in creating liposomes and monolayers for investigating membrane permeability and monolayer viscosity.