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By Target- Apoptosis
- EGFR(1)
- IRAK(1)
- PARP(1)
- PROTACs(1)
- Pim(1)
- Trk receptor(1)
- Others(1)
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Results for "
dpc4
" in TargetMol Product Catalog- Inhibitors & Agonists2
- PROTAC Products1
- Recombinant Protein1
- Antibody Products3
DP-C-4
T36251
DP-C-4 is a Cereblon-based dual PROTAC for simultaneous degradation of EGFR and PARP[1]. DP-C-4 (1-50 μM; 24 hours) has degradation effects on EGFR and PARP simultaneously in a dose-dependent manner in SW1990 cells[1]. [1]. Mengzhu Zheng, et al. Rational Design and Synthesis of Novel Dual PROTACs for Simultaneous Degradation of EGFR and PARP. J Med Chem. 2021 May 26.
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