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dopamine d2 receptor agonist-2

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  • Inhibitors & Agonists
    4
    TargetMol | Inhibitors_Agonists
Dopamine D2 receptor agonist-2
T600751610591-93-9
Dopamine D2 receptor agonist-2 (Dopamine D2 Receptor) is a ligand targeting the dopamine D2 receptor.
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Metoclopramide
5-Chloro-2-methoxyprocainamide
T4616364-62-5
Metoclopramide (5-Chloro-2-methoxyprocainamide) is a dopamine D2 antagonist which has been used for treatment of a variety of gastrointestinal symptoms over the last thirty years. In various countries, metoclopramide is the antiemetic drug of choice in pregnant women. Findings provide reassurance regarding the safety of metoclopramide for the fetus when the drug is given to women to relieve nausea and vomiting during pregnancy. Evidence also supports its use for gastroparesis (poor stomach emptying) and gastroesophageal reflux disease. It appears to bind to dopamine D2 receptors where it is a receptor antagonist, and is also a mixed 5-HT3 receptor antagonist 5-HT4 receptor agonist.
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BP 897
2-Naphthalenecarboxamide, N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-
T9100192384-87-5
BP 897 (2-Naphthalenecarboxamide, N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-) is a potent and selective dopamine D3 receptor agonist, and a weak dopamine D2 receptor antagonist, with Kis of 0.92 nM and 61 nM for D3 and D2 receptors, and shows low affinities at D1 and D4 receptors (Kis, 3 and 0.3 μM, respectively).
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unc9994 hydrochloride
T628532108826-33-9
UNC9994 hydrochloride is a functionally selective, β-arrestin-biased dopamine D2 receptor (D2R) agonist (Ki: 79 nM) that selectively activates β-arrestin recruitment and signal transduction. UNC9994 hydrochloride is a Gi-regulated antagonist of cAMP production and a partial agonist of the D2R β-arrestin-2 interaction, exhibiting psychostimulatory effects.
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8-10 weeks
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