dimethyl fumarate

Dimethyl fumarate (DMF) is an Nrf2 activator with oral activity and blood-brain barrier permeability. Dimethyl fumarate has antimicrobial, anti-inflammatory, and immunomodulatory activities and has been used in the study of multiple sclerosis.

Dimethyl fumarate D6 is a deuterium labeled Dimethyl fumarate. can induces upregulation of antioxidant gene expression.

Dimethyl Fumarate-2,3-d2 is a deuterated compound of Dimethyl Fumarate. Dimethyl Fumarate has a CAS number of 624-49-7. Dimethyl fumarate, a fumarate derivative, is used as antiinflammatory and immunomodulatory agent.

Dimethyl fumarate (Standard) is a reference standard for dimethyl fumarate, suitable for quantitative analysis, quality control, and biochemical experiments. Dimethyl fumarate is an Nrf2 activator with oral bioavailability and blood-brain barrier permeability, exhibiting antibacterial, anti-inflammatory, and immunomodulatory activities.

Monomethyl fumarate is a potent agonist of GPR109A .

GTCpFE, a compound synthesized from Dimethyl fumarate (DMF) and Aspirin (ASA), inhibits IKKα/β in the NF-κB pathway, exhibiting anti-inflammatory activity by preventing p65 from entering the nucleus. It selectively inhibits cancer stem cell (CSC) activity by reducing the growth of mammospheres and the expression of the CD44+CD24- immune phenotype. Furthermore, GTCpFE targets breast cancer stem cells, crucial in aggressive cancer phenotypes that depend on NFκB and PGE2.

Amfepentorex fumarate was marketed as an appetite suppressant.

Monomethyl fumarate-d2 is the deuterated form of Monomethyl fumarate, which is an active metabolite of Dimethyl fumarate (DMF) and serves as an effective GPR109A agonist. Monomethyl fumarate holds potential in various neuroprotective pathways and models of other retinal diseases.