deet

Diethyltoluamide (DEET) is the most common active ingredient in insect repellents.

ω-Hydroxy-DEET, a significant metabolite of the insect repellent N-N-diethyl-meta-toluamide (DEET), exhibits anti-proliferative properties. DEET, renowned for being a spatial repellent and irritant, is frequently employed to deter mosquito contact.

Deethylindanomycin is a polyether antibiotic that has been found in S. setonii. It is active against a variety of Gram-positive bacteria, including various strains of S. aureus and Streptococcus, as well as one strain of S. pneumoniae (MICs = 4, 4, and 2 μg ml, respectively). It is also active against coccidia in vitro, inhibiting E. tenella development, but is inactive against E. tenella infection in chicks when administered at a dose of 200 μg g in the diet. Deethylindanomycin acts as an ionophore in lipid bilayer membranes and is more selective for potassium ions than calcium, magnesium, and sodium ions. It induces histamine release from rodent mast cells and human basophils in vitro in a calcium-dependent manner.

2β-Methoxy-2-deethoxy-8-O-deacylphantomolin-8-O-tiglinate is a sesquiterpene lactone that can be isolated from Elephantopus mollis. This compound exhibits cytotoxicity in mouse neuroblastoma B104 cells with an IC50 of 3.85 μM.

DCBA, an endogenous metabolite of the insect repellent N-N-diethyl-meta-toluamide (DEET), is utilized to evaluate DEET exposure through its concentration levels in urine.

Picaridin (Lcaridin) is a topical insect repellent.

Eucamolol exhibits significant repellent activity against Aedes albopictus, and inhibits its feeding as well as DEET, is effective repellent (75%) up to 3 h after exposure to mosquito.