d18:1/6:0

C6 L-erythro Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. It is metabolized by ceramide glucosyltransferase to form C6 L-erythro glucosylceramide. C6 L-erythro Ceramide is cytotoxic to U937 cells (IC50 = 18 μM).

C6 D-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides., C6 D-threo Ceramide is cytotoxic to U937 cells in vitro (IC50 = 18 μM). It is metabolically inactive and, unlike C6 L-erythro ceramide , C6 D-threo ceramide cannot be converted to C6 glucosylceramide by ceramide glucosyltransferase. C6 D-threo Ceramide promotes survival of isolated rat spinal neurons when used at concentrations up to 2.5 μM but induces cell death at concentrations greater than 5 μM. It enhances IL-4 production induced by phorbol 12-myristate 13-acetate in EL4 T cells when used at a concentration of 10 μM.

C6 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. It is cytotoxic to U937 cells in vitro (IC50 = 18 μM), metabolically inactive, and unlike C6 L-erythro ceramide, it cannot be converted to C6 glucosylceramide by ceramide glucosyltransferase. C6 L-threo Ceramide enhances IL-4 production induced by phorbol 12-myristate 13-acetate in EL4 T cells at 10 μM.

N,N-dihexyl Sphingosine (d18:1/6:0/6:0) is a lipid molecule that can be used in life science related research. The CAS number of N,N-dihexyl Sphingosine (d18:1/6:0/6:0) is 2377379-53-6.

C6 Biotin Glucosylceramide (d18:1/6:0) is a lipid molecule that can be used in life science related research. The CAS number of C6 Biotin Glucosylceramide (d18:1/6:0) is 2692623-22-4.

C6 Biotin Ceramide (d18:1/6:0) is a lipid molecule used in life science-related research.

C6 Ceramide (d18:1/6:0) alkyne is an ω-alkyne derivative of C6 ceramide. The terminal alkyne group enables it to participate in click chemistry reactions, facilitating the labeling of C6 ceramide with fluorescent tags or biotin. This allows for analysis of C6 ceramide's metabolism and biological activity.

C14 Ceramide (d18:1/14:0) is an endogenous ceramide produced by ceramide synthetase 6, which can be used for Parkinson's research.

C16 (2'(S)-hydroxy) Ceramide (d18:1/16:0) is a lipid molecule that can be used in life science related research. The CAS number of C16 (2'(S)-hydroxy) Ceramide (d18:1/16:0) is 890041-50-6.

7-Hydroxy-6-isopentylcoumarin is an inhibitor of sphingomyelinase. SM (d18:1/15:0) is utilized in biomedical research focused on sphingolipid metabolism, membrane lipid signaling regulation, and mechanistic studies related to neurodegenerative disease models including Alzheimer’s disease and metabolic syndrome-associated pathways.