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cs-055

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
HDAC-IN-7
T2025743420-02-2
HDAC-IN-7, an analogue of Tucidinostat (Chidamide), is a HDAC inhibitor. HDAC-IN-7 inhibits acetylation of histone protein H3 and induces apoptosis in human colon cancer cell lines[1].
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Tucidinostat
HBI-8000, CS 055, Chidamide
T44811616493-44-7
Tucidinostat (Chidamide) is an effective and orally bioavailable HDAC enzymes class I (HDAC1 2 3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, less active on HDAC8 11 (IC50: 733 432 nM), and shows no effect on HDAC4 5 6 7 9.
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