creatine (standard)

Creatine (Standard) is a naturally occurring nitrogenous organic acid that is stored in the body primarily as Creatine Phosphate, an important source of rapid intracellular energy supply.Creatine has neuroprotective and cardiovascular protective effects, and exerts anti-inflammatory activity through inhibition of TNF-alpha expression. As a standard, Creatine can be used for quantitative analysis to study energy metabolic pathways and related diseases.

Guanidinoacetic acid (Standard) is methylated in the liver to creatine and is involved in the regulation of energy metabolism that can be used as a standard for quantitative assays to study the creatine synthesis pathway, inherited metabolic disorders (e.g., guanidinoacetic acid methyltransferase deficiency), neurological disorders, and as a nutritional supplement to enhance athletic performance.Guanidinoacetic acid is a regulator of AMP-activated protein kinase (AMPK), can act as an inhibitor to down-regulate miR - 133a expression, and is an antagonist of the GABAC receptor.