cp45899

Sulbactam (CP45899) is a semi-synthetic beta-lactamase inhibitor. The beta-lactam ring of sulbactam irreversibly binds to beta-lactamase at or near its active site, thereby blocking enzyme activity and preventing metabolism of other beta-lactam antibiotics by the enzyme. Combining this agent with a beta-lactamase susceptible antibiotic, such as penicillins or a cephalosporin, to treat infections caused by beta-lactamase producing organisms, results in a decreased turnover rate of the beta-lactamase sensitive antibiotic and enhances its antibacterial activity.

Sulbactam sodium (CP-45899-2) (Unasyn) is an irreversible β-lactamase inhibitor.

Sulbactam-d2(sodium) is the deuterated form of Sulbactam sodium. Sulbactam (CP45899) sodium is a competitive, irreversible β-lactamase (beta-lactamase) inhibitor. It exhibits antibacterial activity by inhibiting the multidrug-resistant Acinetobacter baumannii-Acinetobacter complex.

Sulbactam-d5 (sodium) is the deuterated analog of Sulbactam sodium. Sulbactam (CP45899) sodium acts as a competitive, irreversible inhibitor of β-lactamase. It exhibits antibacterial properties and is effective against multi-drug resistant Acinetobacter baumannii-Acinetobacter calcoaceticus complex.