copper chelator

Neocuproine is a copper(I) chelator that enhances the purinergic component of vasoconstriction induced by electric field stimulation, and is often used as a ligand reagent and copper ion detector.Neocuproine forms stable complexes with copper ions and can play a catalytic role in certain chemical reactions and analytical methods.Neocuproine acts as a redox-active on the iron and cobalt ligand platform for protection against oxidative damage in NSC34 cells.

DOTA-ADIBO TFA is a DOTA-derived bifunctional chelating agent (BFC) that facilitates drug conjugation through a catalyst-free, copper-free click reaction. It enables the construction of fusion chelator systems, and after Cu[64] modification, it is used for the synthesis of radiotracers. It is applied in positron emission tomography (PET) imaging of tumors expressing integrin αvβ6.