copolymers

N-(2-Hydroxypropyl)methacrylamide is utilized in the synthesis of copolymers for the targeted delivery of antileishmanial agents in [Visceral leishmaniasis].

m-PEG-OH (MW 1000) serves as a macromolecular initiator, facilitating the synthesis of amphiphilic block copolymers. These copolymers are utilized to create nanoscale micelles for delivering active drugs. When hydrophobic anti-cancer agent Paclitaxel is encapsulated within these micelles, it demonstrates enhanced activity against cancer cells compared to free Paclitaxel. Additionally, it predominantly accumulates in tumor tissues, with only limited distribution in healthy organs.

m-PEG-OH (MW 10000) serves as a macromolecular initiator in the synthesis of amphiphilic block copolymers, which can be used to create nanoscale micelles for delivering active drugs. These micelles encapsulate the hydrophobic anticancer agent Paclitaxel and exhibit greater efficacy in killing cancer cells compared to free Paclitaxel. Moreover, they preferentially accumulate in tumor tissues while having limited distribution in healthy organs.

Poly(ethylene glycol) dithiol (Mn 1500) is a thiol-modified PEG utilized for synthesizing dithiol-terminated amphiphilic diblock copolymers, which are applicable in drug delivery.

Mal-PEG-OH (MW 2000) serves as a macromolecular initiator for the ring-opening polymerization of LA to produce amphiphilic diblock copolymers. These amphiphilic block copolymers are used to prepare nanoparticles, forming an active drug delivery system. The nanoparticles can encapsulate Triptolide , addressing its poor water solubility and reducing its toxicity.

Mal-PEG-OH (MW 10000) (Maleimide-PEG-Hydroxy (MW 10000)) is a linear heterobifunctional PEG compound featuring maleimide and hydroxy groups. It can serve as a macromolecular initiator to obtain amphiphilic diblock copolymers via the ring-opening polymerization of Lactate (Lactic Acid). These amphiphilic block copolymers are used to create nanoparticles, forming an active drug delivery system.

Mal-PEG-OH (MW 40000) (Maleimide-PEG-Hydroxy (MW 40000)) is a linear heterobifunctional PEG product featuring maleimide and hydroxy groups. This compound can serve as a macromolecular initiator to generate amphiphilic diblock copolymers through the ring-opening polymerization of Lactate (Lactic Acid). Such amphiphilic block copolymers are utilized in forming nanoparticles for active drug delivery systems.

Mal-PEG-OH (MW 3400) (Maleimide-PEG-Hydroxy (MW 3400)) is a linear heterobifunctional PEG product featuring maleimide and hydroxyl groups. This compound can act as a macromolecular initiator to synthesize amphiphilic diblock copolymers through the ring-opening polymerization of Lactate (Lactic Acid). Such amphiphilic block copolymers can be used to prepare nanoparticles, forming an active drug delivery system.

Mal-PEG-OH (MW 20000) (Maleimide-PEG-Hydroxy (MW 20000)) is a linear heterobifunctional PEG product featuring maleimide and hydroxy groups. This compound can be used as a macromolecular initiator to form amphiphilic diblock copolymers through the ring-opening polymerization of Lactate (Lactic Acid). Such amphiphilic block copolymers are utilized to create nanoparticles, forming an active drug delivery system.

Lactyl-CoA is an acyl-CoA, and the sulfhydryl group of its coenzyme A undergoes a condensation reaction with the carboxyl group of lactic acid, which can be used for the synthesis of biodegradable materials of lactate-based copolymers.

m-PEG-OH (MW 20000) can serve as a macromolecular initiator and participate in the synthesis of amphiphilic block copolymers. These copolymers can be used to prepare nanoscale micelles for delivering active drugs. The micelles encapsulate the hydrophobic anticancer agent Paclitaxel , enhancing its ability to kill cancer cells compared to free Paclitaxel. Additionally, the micelles preferentially accumulate in tumor tissues while showing limited distribution in healthy organs.