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Results for "

chop

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  • Inhibitors & Agonists
    26
    TargetMol | Inhibitors_Agonists
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Cannabigerol
TN146525654-31-3
Cannabigerol is a high affinity α±2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; also binds to the CB2 receptor; it can relieve interocular pressure, which may be of benefit in the treatment of glaucoma.
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Trichophydine
T124429
Trichophydine is a useful organic compound for research related to life sciences and the catalog number is T124429.
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Isorhynchophylline
Isorhyncophylline, Isorhychophylline, IsoRhy, 7-Isorhyncophylline
T6S06576859-01-4
1. Isorhynchophylline (7-Isorhyncophylline) and rhyncophylline can directly inhibit the contractile responses induced by several agonists in small blood vessels of rat, they also can inhibit the hypertensive effect of angiotensin Ⅱ.
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Isorhynchophyllic acid
T125852
Isorhynchophyllic acid is a useful organic compound for research related to life sciences and the catalog number is T125852.
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Rhynchophylline
Rhyncophylline, Rhynchophyllin, Mitrinermine, Mitrinermin
T6S065976-66-4
1. Rhynchophylline (Mitrinermine) can protect against ischemic damage, probably via regulating the Akt mTOR pathway. 2. Rhynchophylline can protect against glutamate-induced neuronal death, can inhibit MA impairment in cultured neurons in vitro. 3. Rhynchophylline and isorhynchophylline have a non-competitive antagonistic effect on the NMDA-type ionotropic glutamate receptors, suggest that these alkaloids exert their protective action against ischemia-induced neuronal damage by preventing NMDA, muscarinic M1, and 5-HT2 receptors-mediated neurotoxicity during ischemia.
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Oroxylin A
6-Methoxybaicalein, Baicalein 6-methyl ether
T6S1315480-11-5
1. Oroxylin A (Baicalein 6-methyl ether) has various anti-tumor effects including apoptosis, cell cycle arrest, drug-resistant reversion. 2. Oroxylin A possesses abilities of inhibiting the ATRA-induced IL-6 production via modulation of LAP LIP CHOP in leukemia cell lines, which could providing a therapeutic strategy for RAS. 3. Oroxylin A inhibits UCP2s triggers the MPTP opening, and promotes the apoptosis in CaCo-2 cells; uncoupling protein 2 plays a key role in mitochondrial apoptotic pathway. 4. Oroxylin A inhibits N1ICD translocating to the nucleus and binding to epithelial-mesenchymal transition-related transcription factor Snail, thus suppressing the invasion and migration of MCF-7 cells. 5. Oroxylin A improves the sensitivity of K562 ADM cells by increasing apoptosis in leukemic cells and decreasing the expression of CXCR4 and PI3K Akt NF-κB pathway, and probably served as a most promising agent for CML treatment.
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TargetMol | Citations Cited
Bufotalin
Bufotaline
T5A2461471-95-4
1. Bufotalin (Bufotaline)e is a kind of poisonous secretions of toads.
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