chain

Metformin (1,1-Dimethylbiguanide) is an AMPK activator with blood-brain barrier permeability. Metformin may improve glycemic control by increasing insulin sensitivity and decreasing intestinal glucose uptake, and is commonly used in type 2 diabetes research.

Metformin hydrochloride (1,1-Dimethylbiguanide hydrochloride), a widely used anti-diabetic drug, exhibits potential anti-Y properties by inhibiting the proliferation of various Y cells, including colon and prostate.

N-Boc-4-pentyne-1-amine is an alkyl chain-based PROTAC linker compound used in the synthesis of PROTAC MG-277 [1].

MPP+ iodide, the metabolite of a neurotoxin MPTP, causes symptom of Parkinson's disease (PD) in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ induces dopamine transporter (DAT) externalization in dopaminergic (DA) neurons, but internalization of serotonin transporter (SERT) in serotonergic (5-HT) neurons. MPP+ induces autophagic cell death in SH-SY5Y cells.

8-[(2,6-dimethylbenzyl)amino]-2,3-dimethylimidazo[1,2-a]pyridine-6-car is a H+ K+ ATPase inhibitor with IC50 of 0.38μM.

Hydrocarbon chain derivative 1 has inhibitory activities against lipid synthesis.

IgG has four forms, provides the majority of antibody-based immunity against invading pathogens. The only antibody capable of crossing the placenta to give passive immunity to the fetus. Eliminates pathogens in the early stages of B cell-mediated (humoral

Immunoglobulin light chain variable region fragment [Homo sapiens] is a fragment (Phe-Thr-Leu-Lys-Ile-Ser-Arg) on the variable region of the human immunoglobulin light chain.

Insulin β Chain Peptide (15-23), also referred to as INS, is an insulin-derived peptide specifically recognized by islet-associated T cells. The tetramer of Insulin β Chain Peptide (15-23) effectively stained the INS-reactive CTL clone G9C8; however, neither this tetramer nor the negative control tetramer (TUM) stained splenic CD8+ T cells from NOD or 8.3-TCRαβ transgenic NOD mice.

MyosinH Chain Fragment, mouse is a fragment derived from the α-myosin heavy chain peptide and can be used to induce experimental autoimmune myocarditis (EAM) in mouse models.

Myosin H Chain Fragment, mouse acetate salt is a peptide segment derived from the α-myosin heavy chain and is used to induce experimental autoimmune myocarditis (EAM) in mice.

Myosin light chain kinase fragment 11-19 amide (MLCK(11-19) amide) acts as a substrate-specific peptide inhibitor of MLCK and inhibits hypotonicity-induced Ca2+ entry, with applications in human cervical cancer research [1] [2].

Anti-RatFcRnheavy chain heterodimers Antibody (1G3) is a mouse-derived antibody, specifically targeting the FcRn heavy chain heterodimers. The isotype control for Anti-RatFcRnheavy chain heterodimers Antibody (1G3) is designated as MouseIgG1kappa, Isotype Control.

Anti-Rat Kappa Immunoglobulin Light Chain Antibody (MAR 18.5) is an IgG2a, κ antibody inhibitor derived from mice and specifically targets the rat κ immunoglobulin light chain.

Anti-Clathrin Heavy Chain Antibody is a human-source antibody expressed in CHO cells, specifically targeting the Clathrin Heavy Chain. For isotype control, please refer to Human IgG1 kappa, Isotype Control.

This peptide is a fragment of the alpha-chain of insulin amino acids 1 to 13. The insulin a-chain epitope recognized by human T cells is posttranslationally modified.

Thrombin is a trypsin-like serine protease that is encoded by the F2 gene in humans. Thrombin is produced by the enzymatic cleavage of two sites on prothrombin by activated Factor X (Xa). Thrombin in turn acts as a serine protease that converts soluble

Ferritin is a protein of 450 kDa consisting of 24 subunits that is present in every cell type. Invertebrates, these subunits are both the light (L) and the heavy (H) type with an apparent molecular weight of 19 kDA or 21 kDA respectively. The ferritin fou

Immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus] is a fragment on the variable region of the human and mouse immunoglobulin light chain. Immunoglobulins (Ig) are the antigen recognition molecules of B cells. An Ig molecule

Immunoglobulin M heavy chain (IGHM) fragment [Homo sapiens] is a fragment (Gly-Val-Ala-Leu-His-Arg-Pro-Asp-Val-Tyr-Leu-Leu-Pro-Pro-Ala-Arg) on the human immunoglobulin micro heavy chain. Immunoglobulins (Ig) are the antigen recognition molecules of B cell

Mid-chain triglyceride of caprylic caproic acid serves as a co-solvent.

2,3,4,6-Tetra-O-acetyl-PtdGlc(di-acyl Chain) is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

6-OAc PtdGlc(di-acyl Chain) is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

Rotenone is a natural plant-derived insecticide that acts as an inhibitor of mitochondrial electron transport chain complex I. It promotes the generation of mitochondrial reactive oxygen species, induces apoptosis, and is commonly used to establish Parkinson's disease models.