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(2)
By Target- Epigenetic Reader Domain
- Histone Acetyltransferase(2)
- PROTACs(2)
- PSMA(1)
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Results for "
cbp/p300, prostate cancer cell
" in TargetMol Product Catalog- Inhibitors & Agonists4
- PROTAC Products2
Piflufolastat
DCFPYL
T312241423758-00-2In house
Piflufolastat (DCFPYL) is a PET imaging agent for prostate cancer PSMA. It is a fluorinated prostate-specific membrane antigen (PSMA) preparation. Piflufolastat can be used to prepare piflufolastat F 18 (DCFPyL F-18).
- $52
Size
QTY
CBPD-409
T209572
CBPD-409 is an orally active CBP/p300 degrader with a DC50 of 0.2–0.4 nM. It exhibits antiproliferative effects in AR+ prostate cancer cell lines VCaP, LNCaP, and 22Rv1, with an IC50 of 1.2–2.0 nM. Additionally, CBPD-409 shows antitumor activity.
Inquiry
CBPD-268
T209630
CBPD-268 is an effective orally active CBP/p300 PROTAC degrader, with a DC50 value of ≤ 0.03 nM. It induces degradation of CBP/p300 and inhibits cell growth, exhibiting antitumor activity. Additionally, CBPD-268 shows potential for research in AR-positive prostate cancer.
Inquiry
I-CBP112 hydrochloride
T42472147701-33-3
I-CBP112 is a selective inhibitor of the bromodomain-containing transcription factors. I-CBP112 (1 mM) has little activity against other bromodomains. I-CBP112 targets the CBP/p300 bromodomains. I-CBP112 significantly reduced the leukemia-initiating poten
- $83
Size
QTY
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