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c-fms-in-3

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  • Inhibitors & Agonists
    5
    TargetMol | Inhibitors_Agonists
c-Fms-IN-3
T10649885704-21-2In house
c-Fms-IN-3 is a novel inhibitor of c-FMS, suitable for research on antirheumatic and anti-inflammatory diseases.
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6-8weeks
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TargetMol | Inhibitor Sale
osi-930
OSI 930
T2624728033-96-3
OSI-930, an orally active inhibitor of c-Kit and the vascular endothelial growth factor receptor-2 (VEGFR-2), targets cancer cell proliferation and blood vessel growth (angiogenesis) in tumors.
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Lestaurtinib
CEP 701, KT5555, KT 5555, CEP-701, KT-5555, CEP701
T15738111358-88-4
Lestaurtinib (CEP 701) is an orally available and selective inhibitor of FMS-like tyrosine kinase-3 (FLT3, IC50: 0.9 nM), which inhibits FLT3 autophosphorylation in vitro.Lestaurtinib promotes the expression of c-MYC, inhibits the phosphorylation of RPTKs, and has high affinity for TrkA and JAK2. Lestaurtinib promotes c-MYC expression, inhibits phosphorylation of RPTKs, has a high affinity for TrkA and JAK2, induces apoptosis and cell growth arrest, and can be used to study leukemia.
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7-10 days
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SKLB4771
FLT3-​IN-​1, FLT3-IN-1
T20511370256-78-2
SKLB4771 (FLT3-IN-1) is a novel potent and selective Flt3 inhibitor.
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Midostaurin
PKC412, N-Benzoylstaurosporine, CGP41231, CGP 41251
T3211120685-11-2
PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c-kit, platelet-derived growth factor receptor (PDGFR) and FMS-like tyrosine kinase 3 (FLT3) tyrosine kinases, which may result in disruption of the cell cycle, inhibition of proliferation, apoptosis, and inhibition of angiogenesis in susceptible tumors.
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