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By Target- Bcl-2 Family
- Microtubule Associated(1)
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Results for "
btb-1
" in TargetMol Product Catalog- Inhibitors & Agonists3
- PROTAC Products1
- Recombinant Protein3
BTB-1
BTB 1, NSC156750
T402986030-08-2
BTB-1 (NSC156750) is a novel small molecule inhibitor of the mitotic motor protein Kif18A.
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Keap1-IN-1
T204622
Keap1-IN-1 (Compound 27) is an inhibitor of Keap1, functioning by covalently modifying the Cys151 residue on the BTB domain of KEAP1, thereby disrupting the interaction between Keap and Nrf. It enhances the mRNA expression of the antioxidant response element (ARE) dependent gene NQO1, with an EC50 of 160 nM, and exhibits cytotoxicity in U2OS cells, with an EC50 of 527 nM.
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BI-3802
T54082166387-65-9
BI-3802, a highly potent BCL6 degrader, targets and inhibits the Bric-à-brac (BTB) domain of BCL6, exhibiting an IC50 value of ≤3 nM. It induces polymerization of BCL6 and facilitates its degradation in a manner dependent on the E3 ligase SIAH1, demonstrating notable antitumor activity[1][2].
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