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Search Results for " bone "

Targets

253

Compounds

90

Natural Products

525

Recombinant Proteins

5

Libraries

Cat No. Product Name Synonyms Targets
T1973 PFI-4 PFI4 Epigenetic Reader Domain
PFI-4 is a potent and selective and cell-permeable BRPF1 bromodomain inhibitor.
T1850 Balicatib AAE581 Cysteine Protease
Balicatib (AAE581) is a potent and selective inhibitor of cathepsin K, used in trials studying the treatment of osteoporosis.
T22702 CYM 50769 Neuropeptide W
CYM 50769 is a neuropeptide W/B receptor 1 (NPBWR1, GPR7) antagonist(IC50 = 0.12 μM). CYM 50769 inhibited NPW activation of NPBWR1 with a submicromolar IC50, and displayed high selectivity against a broad array of off-ta...
T7469 Alendronic Acid alendronate Others
Alendronic Acid (alendronate) is a nonhormonal medication used for osteoporosis, osteogenesis imperfecta, and several other bone diseases.
T8550 NDMC101 Others , NF-κB , Proteasome
NDMC101 is an inhibitor of dipeptidyl peptidase-IV activity in human T cells and exhibits immunomodulatory effects. It also acts as a novel inhibitor of NFATc1 and NF-κB activity.
T38776 LP-922056 Wnt/beta-catenin
LP-922056 is an inhibitor of Notum Pectinacetylesterase with EC50 values of 21 nM, 55 nM for human and mouse, respectively.
T39508 KY-02327 Others
KY-02327, a metabolically stabilized analog of KY-02061, serves as a potent inhibitor of the Dishevelled (Dvl)-CXXC5 interaction. This compound activates the Wnt/β-catenin pathway, thereby promoting osteoblast differenti...
T2121 SW033291 Dehydrogenase
SW033291 is a small-molecule inhibitor of 15-PGDH (Ki=0.1 nM) that increases prostaglandin PGE2 levels in bone marrow and other tissues.
T21616 L-006235 L 006235 Cysteine Protease
L-006235 is a potent and reversible inhibitor of cathepsin K with IC50 of 0.25 nM.
T1867 Otenaproxesul ATB 346 Apoptosis , COX
Otenaproxesul (ATB 346) is a novel hydrogen sulphide-releasing derivative of naproxen with markedly reduced toxicity.
T8645 PF-06446846 Others
PF 06446846 is a potent and selective PCSK9 inhibitor
T16159 Muramyl dipeptide MDP NOD
Muramyl dipeptide (MDP) is a synthetic immunoreactive peptide, consisting of N-acetyl muramic acid attached to a short amino acid chain of L-Ala-D-isoGln. Muramyl dipeptide indirectly decreases osteoclast differentiation...
T2334 Avanafil TA1790 PDE
Avanafil (TA1790) is a selective inhibitor of phosphodiesterase type 5 (PDE5) and is used as therapy of erectile dysfunction.
T6574 Lumiracoxib Prexige,COX-189 COX
Lumiracoxib (Prexige) is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. Phase 4.
T13324 VUF11207 fumarate CXCR , Arrestin
VUF11207 fumarate is an agonist of CXCR7 and a high-potency ligand of CXCR7 (pKi: 8.1).
T23383 SR11237 SR 11237 Others , RAR/RXR 
SR11237 is a Pan retinoid X receptor (RXR) agonist. SR11237 causes RXR/RXR homodimers to form and transactivate a reporter gene containing a RXR-response element.
T1817 GNF-2 GNF2 SARS-CoV , Bcr-Abl
GNF-2 is a highly selective non-ATP competitive inhibitor of Bcr-Abl.
T23146 PHA 568487 free base PHA 568487 AChR
The quinuclidine PHA 568487 free base is an agonist of the alpha 7 nicotinic acetylcholine receptor that was designed to mitigate the bioactivation associated with the core scaffold and subsequently remove associated lia...
T6451 Clodronic acid disodium salt Loron,Clodronate Disodium,Lodronate Others
Clodronic acid disodium salt (Lodronate), a bisphosphonate, is a potent antiosteolytic agent which inhibits bone resorption.
T1944 LDN-214117 ALK , TGF-beta/Smad
LDN-214117 is a potent and selective ALK2 inhibitor.
T21460 Teriparatide acetate hPTH 1-34 (acetate salt),Parathar acetate,Forteo Others
Teriparatide acetate (Forteo) is a PHT agonist, with an IC50 of 2 nM in HEK293 cells.Teriparatide acetate is a recombinant form of parathyroid hormone. It is an effective anabolic (i.e., bone growing) agent used to treat...
T6374 Alfacalcidol Bondiol,Etalpha,1-hydroxy Vitamin D3,1.alpha.-Hydroxyvitamin D3,1-hydroxycholecalciferol Others
Alfacalcidol (Etalpha) (1-hydroxycholecalciferol; Alpha D3; 1.alpha.-Hydroxyvitamin D3) is a non-selective VDR activator medication.
T15259 Evatanepag CP-533536 free acid Prostaglandin Receptor
Evatanepag (CP-533536 free acid) is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM.CP-533536 demonstrated the ability to heal fractures when administered l...
T7566 GRGDSPK EMD 56574 Others
GRGDSPK (EMD 56574) is an inhibitory peptide for RGD-mediated adhesion between integrin and extracellular matrix molecules.
T1925 PLX647 c-Fms , c-Kit
PLX647 is a highly selective dual FMS/KIT kinase inhibitor (IC50: 28/16 nM).
T9026 MEISi-2 Benzoic acid, 4-hydroxy-, 2-[(Z)-(2-oxo-1(2H)-naphthalenylidene)methyl]hydrazide Others
MEISi-2 is a potent MEIS inhibitor (MEISi). MEISi-2 significantly inhibits MEIS-luciferase reporters in vitro.
T29978 Amicibone Amicibono
Amicibone is a biochemical.
T8400 Pamidronic acid Wnt/beta-catenin
Pamidronic acid Leads to Bone Necrosis via Suppression of Wnt/β-Catenin Signaling in Human Bone Marrow Mesenchymal Stem Cells
T0308 Etidronic acid HEDPA,Etidronate,HEDP Apoptosis , Phosphatase , Others , HBV
Etidronic acid (HEDP) is a diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
T13911 Tacalcitol monohydrate Curatoderm monohydrate,TV 02 monohydrate,TV-02H monohydrate,1,24(R)-Dihydroxyvitamin D3 monohydrate Cysteine Protease
Tacalcitol monohydrate(Curatoderm monohydrate), a vitamin D3 analog that promotes bone development by regulating calcium ions, can be used to study psoriasis.
T0575 1-Methylimidazole Others
1-Methylimidazole is a metabolite of 1-methyl-2-thioimidazole (methimazole) which inhibits bone resorption.
T0379 Risedronic Acid Risedronate Others , Transferase
Risedronic Acid (Risedronate), a pyridinyl biphosphonate, can inhibit osteoclast-mediated bone resorption.
T9603 MNITMT
MNITMT is a potent immunosuppressive agent without bone marrow toxicity [1].
T77581 KM02894 GluR
KM02894 is a glutamate release inhibitor. Cancer cells release high levels of glutamate that can disrupt normal bone turnover, which can lead to cancer-induced bone pain.KM02894 may be used in the study of tumor-related ...
T1641 Strontium ranelate Distrontium renelate,S12911 Calcium Channel , CaSR
Strontium ranelate (S12911), a strontium (II) salt of the ranelic acid, is a medication for osteoporosis. Studies indicate it can also slow the course of osteoarthritis of the knee. The drug is unusual in that it both in...
T19415 Medronic acid Methylenediphosphonic acid Others
Medronic acid (Methylenediphosphonic acid), a methylene-substituted bisphosphonate, exhibits affinity for and adherence to hydroxyapatite crystals within the bone matrix. Accumulating at sites of osteoid mineralization, ...
T25492 Hepln-13 Hepln 13,Hepln13 c-Met/HGFR
Hepln-13 is a hepsin inhibitor that acts by hindering prostate cancer bone metastasis.
T0309 Ipriflavone Osteofix advanced glycation end products
Ipriflavone (Osteofix) (Osteofix) is a feed additive and a catabolic agent. It is used to inhibit bone resorption.
T8489 Minodronic acid monohydrate Transferase
Minodronic acid monohydrate is an farnesyl diphosphate synthase inhibitor that acts as a bone resorption inhibitor.
T6373 Alendronate sodium hydrate G-704650,Alendronate,MK 217,Alendronate sodium trihydrate,G-704650 Adronat,Fosamax Transferase
Alendronate sodium hydrate (MK 217) is a nitrogen-containing bisphosphonate, which is an effective inhibitor of bone resorption. It is utilized for the treatment and prevention of osteoporosis.
T39024 PrNMI Cannabinoid Receptor
PrNMI is a highly effective and orally active agonist targeting the peripherally restricted cannabinoid 1 receptor (CB1R). It exhibits pronounced analgesic properties, efficiently suppressing both chemotherapy-induced pe...
T7809L Ipamorelin 2 Pivalic acid NNC-26-0161 Others
Ipamorelin 2 Pivalic acid (NNC-26-0161) is a growth-hormone-releasing peptide, induces longitudinal bone growth in rats.
T4662 SJ000291942 TGF-beta/Smad
SJ000291942 is an activator of the canonical bone morphogenetic proteins (BMP) signaling pathway.
T2188 Thonzonium Bromide Proton pump , Antibacterial , Autophagy
Thonzonium bromide is a mono-cationic surfactant that is structurally similar to Farnesol as an antimicrobial agent. It inhibits proton transport in a dose-dependent manner (EC50=69 μM). It inhibits RANKL-induced osteocl...
T20112 Triphenyl bismuth NSC 465,NSC-465,NSC465 Others
Triphenyl bismuth (NSC-465) is an additive for making biomedical resins visible on x-ray images and can be used as a radiopaque agent for orthopaedic bone cements.
T7566L1 GRGDSPK acetate GRGDSPK acetate(111119-28-9 Free base) Beta Amyloid
GRGDSPK acetate shows inhibitory activity against integrin-fibronectin binding and can be used in research on integrins in bone formation and resorption.
T6112 Doxercalciferol TSA 840,Hectorol,1.alpha.-Hydroxyvitamin D2,1α-hydroxyvitamin D2 Others
Doxercalciferol (TSA 840) is a synthetic vitamin D2 analog, suppressing parathyroid synthesis and secretion, used to treat secondary hyperparathyroidism and metabolic bone disease.
T21299 Zoledronic acid monohydrate zoledronate,ZOL 446,CGP 42446,CGP42446A,Zoledronic acid hydrate Apoptosis , Others , Autophagy
Zoledronic acid monohydrate (CGP 42446) is a synthetic imidazole bisphosphonate analog with anti-bone-resorption activity.
T1041 Risedronate Sodium NE 58095 Sodium,Risedronic Acid Sodium HBV , Transferase
Risedronate Sodium (NE 58095 Sodium) is an aminobisphosphonate derivative of etidronic acid and CALCIUM CHANNEL BLOCKER that inhibits BONE RESORPTION and is used for the treatment of OSTEOPOROSIS.
T16859 SBI-425 Others
SBI-425 is an effective and orally bioavailable inhibitor of tissue-nonspecific alkaline phosphatase (TNAP). SBI-425 effectively inhibits TNAP in the vasculature and improves cardiovascular parameters and survival withou...

Compounds

PFI-4
T1973
Synonym: PFI4
Target: Epigenetic Reader Domain
Balicatib
T1850
Synonym: AAE581
Target: Cysteine Protease
CYM 50769
T22702
Synonym:
Target: Neuropeptide W
Alendronic Acid
T7469
Synonym: alendronate
Target: Others
NDMC101
T8550
Synonym:
Target: Others, NF-κB, Proteasome
LP-922056
T38776
Synonym:
Target: Wnt/beta-catenin
KY-02327
T39508
Synonym:
Target: Others
SW033291
T2121
Synonym:
Target: Dehydrogenase
L-006235
T21616
Synonym: L 006235
Target: Cysteine Protease
Otenaproxesul
T1867
Synonym: ATB 346
Target: Apoptosis, COX
PF-06446846
T8645
Synonym:
Target: Others
Muramyl dipeptide
T16159
Synonym: MDP
Target: NOD
Avanafil
T2334
Synonym: TA1790
Target: PDE
Lumiracoxib
T6574
Synonym: Prexige,COX-189
Target: COX
VUF11207 fumarate
T13324
Synonym:
Target: CXCR, Arrestin
SR11237
T23383
Synonym: SR 11237
Target: Others, RAR/RXR 
GNF-2
T1817
Synonym: GNF2
Target: SARS-CoV, Bcr-Abl
PHA 568487 free base
T23146
Synonym: PHA 568487
Target: AChR
Clodronic acid disodium salt
T6451
Synonym: Loron,Clodronate Disodium,Lodronate
Target: Others
LDN-214117
T1944
Synonym:
Target: ALK, TGF-beta/Smad
Teriparatide acetate
T21460
Synonym: hPTH 1-34 (acetate salt),Parathar acetate,Forteo
Target: Others
Alfacalcidol
T6374
Synonym: Bondiol,Etalpha,1-hydroxy Vitamin D3,1.alpha.-Hydroxyvitamin D3,1-hydroxycholecalciferol
Target: Others
Evatanepag
T15259
Synonym: CP-533536 free acid
Target: Prostaglandin Receptor
GRGDSPK
T7566
Synonym: EMD 56574
Target: Others
PLX647
T1925
Synonym:
Target: c-Fms, c-Kit
MEISi-2
T9026
Synonym: Benzoic acid, 4-hydroxy-, 2-[(Z)-(2-oxo-1(2H)-naphthalenylidene)methyl]hydrazide
Target: Others
Amicibone
T29978
Synonym: Amicibono
Target:
Pamidronic acid
T8400
Synonym:
Target: Wnt/beta-catenin
Etidronic acid
T0308
Synonym: HEDPA,Etidronate,HEDP
Target: Apoptosis, Phosphatase, Others, HBV
Tacalcitol monohydrate
T13911
Synonym: Curatoderm monohydrate,TV 02 monohydrate,TV-02H monohydrate,1,24(R)-Dihydroxyvitamin D3 monohydrate
Target: Cysteine Protease
1-Methylimidazole
T0575
Synonym:
Target: Others
Risedronic Acid
T0379
Synonym: Risedronate
Target: Others, Transferase
MNITMT
T9603
Synonym:
Target:
KM02894
T77581
Synonym:
Target: GluR
Strontium ranelate
T1641
Synonym: Distrontium renelate,S12911
Target: Calcium Channel, CaSR
Medronic acid
T19415
Synonym: Methylenediphosphonic acid
Target: Others
Hepln-13
T25492
Synonym: Hepln 13,Hepln13
Target: c-Met/HGFR
Ipriflavone
T0309
Synonym: Osteofix
Target: advanced glycation end products
Minodronic acid monohydrate
T8489
Synonym:
Target: Transferase
Alendronate sodium hydrate
T6373
Synonym: G-704650,Alendronate,MK 217,Alendronate sodium trihydrate,G-704650 Adronat,Fosamax
Target: Transferase
PrNMI
T39024
Synonym:
Target: Cannabinoid Receptor
Ipamorelin 2 Pivalic acid
T7809L
Synonym: NNC-26-0161
Target: Others
SJ000291942
T4662
Synonym:
Target: TGF-beta/Smad
Thonzonium Bromide
T2188
Synonym:
Target: Proton pump, Antibacterial, Autophagy
Triphenyl bismuth
T20112
Synonym: NSC 465,NSC-465,NSC465
Target: Others
GRGDSPK acetate
T7566L1
Synonym: GRGDSPK acetate(111119-28-9 Free base)
Target: Beta Amyloid
Doxercalciferol
T6112
Synonym: TSA 840,Hectorol,1.alpha.-Hydroxyvitamin D2,1α-hydroxyvitamin D2
Target: Others
Zoledronic acid monohydrate
T21299
Synonym: zoledronate,ZOL 446,CGP 42446,CGP42446A,Zoledronic acid hydrate
Target: Apoptosis, Others, Autophagy
Risedronate Sodium
T1041
Synonym: NE 58095 Sodium,Risedronic Acid Sodium
Target: HBV, Transferase
SBI-425
T16859
Synonym:
Target: Others
1 2 3 4 5 6
Cat No. Product Name Synonyms Targets
T5751 Tigogenin Others
Tigogenin is one of steroidal sapogenins which is widely used for synthesizing steroid drugs. It might have protective effect on bone and be helpful in preventing the development of osteoporosis.
T5S2129 Sciadopitysin TNF , NF-κB
Sciadopitysin may prevent the development of diabetic osteopathy, it exerts its therapeutic effects via upregulation of mitochondrial biogenesis.Sciadopitysin shows protective effects on antimycin A-induced toxicity in o...
T5575 Cycloastragenol Cyclogalegenol,Astramembrangenin Epigenetic Reader Domain , Telomerase
Astramembrangenin (Cycloastragenol (Astramembrangenin)) is a triterpenoid saponin compound and a hydrolysis product of the main active ingredient in Astragalus membranaceus. Cycloastragenol (CAG) may have a novel therape...
TN1494 Cimicifugoside H-1 Others
Cimicifugoside H1 shows the protective function to cerebral neuron during cerebral ischemia.
T4S0969 Obtusifolin Antioxidant , NF-κB
1. Obtusifolin has antioxidant properties and improves chemically induced diabetes and its complications by modulation of oxidative stress. 2. Obtusifolin suppresses phthalate esters-mediated bone resorption, thus may be...
T2988 (-)-Epigallocatechin Gallate Epigallocatechol Gallate,EGCG Ferroptosis , Reactive Oxygen Species , HIV Protease , Mitochondrial Metabolism , Endogenous Metabolite , Autophagy
(-)-Epigallocatechin Gallate (EGCG) is an antioxidant polyphenol flavonoid that inhibits telomerase and DNA methyltransferase. (-)-Epigallocatechin Gallate (EGCG) blocks the activation of EGF receptors and HER-2 receptor...
T2902 Costunolide Costus lactone,NSC 106404,Costunolid,(+)-Costunolide Apoptosis , Endogenous Metabolite , Telomerase
Costunolide (Costus lactone) has anti-inflammatory and anti-oxidant properties and mediates apoptosis.
TN7036 N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide (9Z,12Z,15Z)-N-[(3-Methoxyphenyl)methyl]-9,12,15-octadecatrienamide,Macamide Impurity 14 Wnt/beta-catenin
N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide (Macamide Impurity 14) induces osteogenic differentiation and subsequent bone formation of mesenchymal stem cells by activating the canonical Wnt/β-catenin signaling pa...
T5712 Zerumbone Antioxidant , HSV
Zerumbone is a natural monocyclic sesquiterpene first isolated from rhizomes of the wild ginger Z. zerumbet.It has also been shown to have anti-oxidant and anti-inflammatory activities, contributing to immunomodulatory a...
T24744 Rubone
Rubone is the tumor suppressor miRNA-34a modulator that acts by inhibiting the growth of hepatocellular carcinoma.
T0912 Tetracycline hydrochloride NCI-c55561,Tetracycline HCl ribosome , Antibacterial , Antibiotic
Tetracycline hydrochloride (NCI-c55561) is the hydrochloride salt of the tetracycline, a broad-spectrum naphthacene antibiotic produced semisynthetically from chlortetracycline, an antibiotic isolated from the bacterium ...
T13768 (+)-Medicarpin Estrogen/progestogen Receptor
(+)-Medicarpin, a pterocarpan, is an isoflavonoid compound derived from multiple medicinal plant species such as Sophora japonica, Zollernia paraensis, Platymiscium yucatamun, Machaerium aristulatum, and Platymiscium flo...
T3488 Tectorigenin 4',5,7-Trihydroxy-6-methoxyisoflavone,Tectorigenine Apoptosis
Tectorigenin (4',5,7-Trihydroxy-6-methoxyisoflavone) is an O-methylated isoflavone. Tectorigenin Promotes Osteoblast Differentiation and in vivo Bone Healing, but Suppresses Osteoclast Differentiation and in vivo Bone Re...
TN1117 Veraguensin p38 MAPK , NF-κB , Antibiotic , Parasite , Antifection
Veraguensin is derived from Magnolia sp.. Veraguensin inhibits bone resorption and shows high antileishmanial activity.
T2820 Glycitin Glycitein-7-β-O-glucoside,Glycitein 7-O-β-glucoside Others , Influenza Virus , Antibacterial
Glycitin (Glycitein 7-O-β-glucoside), a natural isoflavone isolated from legumes, can promote the proliferation of bone marrow stromal cells and osteoblasts and suppresses bone turnover.
TJS0856 Dalbergin 6-Hydroxy-7-Methoxy-4-Phenylcoumarin Others
1. Dalbergin (6-Hydroxy-7-Methoxy-4-Phenylcoumarin) exhibits similar bone conserving effect against bone-loss as estradiol treatment, it as a therapeutic candidate against postmenopausal osteoporosis. 2. Dalbergin preven...
T3S2312 Poncirin Isosakuranetin-7-neohesperidoside Apoptosis , Others
1. Poncirin (Isosakuranetin-7-neohesperidoside) shows a significant in vitro inhibitory effect on the growth of the human gastric cancer cells, SGC-791, in a dose-dependent manner. 2. Poncirin prevents adipogenesis, enha...
T3004 Batilol Batilolum,Stearyl monoglyceride,Batyl alcohol,1-O-Octadecylglycerol Others , Endogenous Metabolite
Batilol (Stearyl monoglyceride), isolated from shark liver oil, is also present in yellow bone marrow of animals and has been described as an inflammatory agent.
T8103 H-HoArg-OH Endogenous Metabolite , Phosphorylase
H-HoArg-OH, a homologue arginine, is a strong inhibitor of human liver and bone alkaline phosphatase.
T3808 Icariside I Lcariside I,Icariin I,Icarisid I Others
Icariside I (Lcariside I) is isolated from Epimedium herb. It can stimulate osteogenic differentiation of BMSCs and inhibit bone resorption activity of osteoclasts.
T9171 Methenolone enanthate Others
Methenolone enanthate is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of anemia due to bone marrow failure.
T7437 3-(3-Hydroxyphenyl)propionic Acid m-Hydroxyphenylpropionic acid,3-Hydroxyhydrocinnamic acid Others , Endogenous Metabolite
3-(3-Hydroxyphenyl)propionic Acid (m-Hydroxyphenylpropionic acid) is one of the major metabolites of ingested caffeic acid.it inhibited osteoclastogenesis and bone osteoclastic resorptive activity.
T8117 Metenolone acetate Methenolone acetate Others , Androgen Receptor
Metenolone acetate (Methenolone acetate) is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of anemia due to bone marrow failure.
T2980 Chondroitin sulfate Chonsurid,Chondroitin polysulfate MMP , Others , Endogenous Metabolite , NO Synthase
Chondroitin sulfate (Chonsurid) is extracted from shark bone;Store the product in sealed, cool and dry condition
T2845 Imperatorin Ammidin,8-Isoamylenoxypsoralen,8-Isopentenyloxypsoralene,Marmelosin,Pentosalen TRP/TRPV Channel , AChR , AChE , NOD
Imperatorin (8-Isopentenyloxypsoralene) is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.
T6S1966 Curculigoside Curculigoside A Antioxidant , NF-κB , JAK , STAT
1. Curculigoside (Curculigoside A) can prevent bone loss , improve osteogenesis and inhibit osteoclastogenesis of hAFSCs, suggesting its potential use to regulate hAFSC osteogenic differentiation for treating bone disord...
TN3209 3′,4′,7-Trihydroxyflavone  ATPase , Others , p38 MAPK , NF-κB
3'4'7-Trihydroxyflavone can markedly inhibit the receptor activator of nuclear factor kappa B ligand (RANKL) induced osteoclastic differentiation from mouse bone marrow derived macrophages (BMMs), it inhibits osteoclasto...
T5S0662 Gelsemine Gelsemin Antioxidant
1. Gelsemine (Gelsemin) has antitumor activity. 2. Gelsemine has anti-oxidative activity. 3. Gelsemine has anti-hyperlipidemic activity. 4. Gelsemine has marked antinociception in inflammatory, neuropathic and bone cance...
T3S0137 Bavachalcone Antibacterial , Antibiotic
Bavachalcone is a major bioactive compounds isolated from Psoralea corylifolia L. it may be useful as a therapeutic drug for bone resorption-associated diseases.Bavachalcone can protect the endothelial function by increa...
T3924 Astragaloside II Astrasieversianin VIII TGF-beta/Smad
Astragaloside II (Astrasieversianin VIII) is an effective MDR reversal agent and may be a potential adjunctive agent for hepatic cancer chemotherapy. Astragaloside II also induces osteogenic activities, differentiation, ...
T3777 Praeruptorin A (+)-Praeruptorin A CaMK , NF-κB
Praeruptorin A ((+)-Praeruptorin A) has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin and inhibiting the Ca(2+)/calmodulin-CaMKIV-CREB-NFATc1 and/or...
TN1711 Gossypetin Antioxidant , p38 MAPK , MAPK , Antibacterial
Gossypetin, a hexahydroxylated flavonoid extractable from Rhodiola rosea Linn. is a potent MKK3 and MKK6 inhibitor that strongly attenuates the MKK3/6-p38 signaling pathway.Gossypetin exhibits antimutagenic, antiatherosc...
T3S1729 Dihydrolycorine Others
1. Dihydrolycorine-HCL(DL) shows hypotensive effects, it can block alpha 1-adrenoceptors. 2. Dihydrolycorine is an inhibitors of protein synthesis in eukarytic cells, it halts protein synthesis in eukaryotic cells by inh...
T3804 Neomangiferin Mangiferin 7-glucoside Phosphatase
Neomangiferin (Mangiferin 7-glucoside) has beneficial effects on high fat diet-induced nonalcoholic fatty liver disease in rats. Neomangiferin and mangiferin inhibit tartrate-resistant acid phosphatase, a biochemical mar...
T5770 Alisol B RANKL/RANK
Alisol B may be a potential novel therapeutic molecule for bone disorders through targeting the differentiation of osteoclasts as well as their functions. Alisol B also inhibited RANKL-induced expression of NFATc1 and c-...
T3662 Eleutheroside E NF-κB
Eleutheroside E has anti-inflammatory effects by inhibiting NF-κB activities. Eleutheroside E significantly decreases the inflammatory cell infiltration, pannus formation, cartilage damage, bone erosion of CIA mice, the ...
T6316 Calcitriol Topitriol,Rocaltrol,Calcijex,RO215535,1,25-Dihydroxyvitamin D3 Endogenous Metabolite
Calcitriol (1,25-Dihydroxyvitamin D3) is a metabolite of vitamin D and a vitamin D receptor (VDR) agonist (IC50=0.4 nM). Calcitriol increases intestinal absorption of calcium and phosphorus, and increases bone resorption...
TN1918 Medicarpin Apoptosis , BCL , ROS , JNK
Medicarpin, a legume phytoalexin, acts as an estrogen receptor (ER) agonist, can stimulate osteoblast differentiation likely via ERα², promote achievement of peak bone mass, and is devoid of uterine estrogenicity; in add...
T8194L Soy Isoflavone Others
Soy Isoflavone is extracted from the seeds of leguminous plants. The isoflavones in soybeans are natural phytoestrogens, which have good medicinal value and can reduce the incidence of breast cancer in women, relieve men...
T4237 Rubiadin-1-methyl ether Rubiadin 1-methyl ether Anti-infection , NF-κB
Rubiadin-1-methyl ether (Rubiadin 1-methyl ether) is a natural product.It inhibits osteoclastic bone resorption via inhibition on the phosphorylation of NF-κB p65 and the degradation of IκBα as well as decrease in the nu...
T5544 2-Furoic acid Furan-2-carboxylic acid Anti-infection , ATP Citrate Lyase , Endogenous Metabolite , Acyltransferase
2-Furoic acid (Furan-2-carboxylic acid), an orally active selective human cathepsin K inhibitor, may have the therapeutic potential for the treatment of diseases characterized by excessive bone loss including osteoporosi...
T3674 Hydroxysafflor yellow A HSYA,Safflomin A TGF-beta/Smad
Hydroxysafflor yellow A (Safflomin A) inhibited adipogenesis by increasing HSL promoter activities. Hydroxysafflor yellow A can effectively protect the liver from long-term alcohol injury by enhancing antioxidant capacit...
T2698 Asperosaponin VI Akebia saponin D,Asperosaponin Ⅵ Apoptosis , Others , Caspase
Asperosaponin VI (Akebia saponin D) , the most abundant constituent of the rhizome of Dipsacus asper, has been used for the treatment of lower back pain, traumatic hematoma and bone fractures.
TN1215 (2S)-2'-Methoxykurarinone 2'-Methoxykurarinone,2'-O-Methylkurarinone Akt , Antifection
(2S)-2'-Methoxykurarinone is isolated from the roots of Sophora flavescens. (2S)-2'-Methoxykurarinone has anti-inflammatory, antipyretic, antidiabetic, and antineoplastic effects. (2S)-2'-Methoxykurarinone inhibits osteo...
T2818 Methyl Vanillate Reactive Oxygen Species , Wnt/beta-catenin , Endogenous Metabolite
Methyl vanillate is Hovenia Dulcis Thunb extract and its ingredient methyl vanillate activate Wnt/β-catenin pathway and increase bone mass in growing or ovariectomized mice. Methyl vanillate is considered to be a slightl...
T1549 Raloxifene hydrochloride LY156758 hydrochloride,Raloxifene HCl,LY139481 hydrochloride,Keoxifene hydrochloride,LY156758 (Keoxifene) HCl Estrogen Receptor/ERR , Others , MAO , Estrogen/progestogen Receptor , Autophagy
Raloxifene hydrochloride (LY156758 hydrochloride) is a second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. It has estrogen agonist effects on bone and chol...
T6S0139 Neobavaisoflavone Apoptosis , DNA/RNA Synthesis
1. Neobavaisoflavone is isolated as a DNA polymerase inhibitor. 2. Neobavaisoflavone might be a potential anabolic agent to treat bone loss-associated diseases. 3. Neobavaisoflavone has anti-inflammatory activity, can si...
T20089 ATP Atipi,ATP disodium salt hydrate,Triphosphoric acid adenosine ester,Ara-ATP,Triphosphaden,Adenosine triphosphate;Ara-ATP,Adenosine triphosphate Endogenous Metabolite
ATP (Adenosine triphosphate) provides cellular energy, participates in overall energy balance, and maintains intracellular homeostasis. ATP can act as an extracellular signaling molecule through interactions with specifi...
T4S1050 Pristimerin Celastrol methyl ester NF-κB , Antibacterial
1. Pristimerin (Celastrol methyl ester) has anticancer activity , treatment with Pristimerin may be a potential strategy for the suppression of hypoxia-induced metastasis through the reversal of hypoxia-induced stem cell...
T3O2749 L-Leucine (S)-Leucine,Leu mTOR
L-Leucine ((S)-Leucine) is one of nine essential amino acids in humans (provided by food), L-Leucine is important for protein synthesis and many metabolic functions. L-Leucine contributes to regulation of blood-sugar lev...
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Natural Products

Tigogenin
T5751
Synonym:
Target: Others
Sciadopitysin
T5S2129
Synonym:
Target: TNF, NF-κB
Cycloastragenol
T5575
Synonym: Cyclogalegenol,Astramembrangenin
Target: Epigenetic Reader Domain, Telomerase
Cimicifugoside H-1
TN1494
Synonym:
Target: Others
Obtusifolin
T4S0969
Synonym:
Target: Antioxidant, NF-κB
(-)-Epigallocatechin Gallate
T2988
Synonym: Epigallocatechol Gallate,EGCG
Target: Ferroptosis, Reactive Oxygen Species, HIV Protease, Mitochondrial Metabolism, Endogenous Metabolite, Autophagy
Costunolide
T2902
Synonym: Costus lactone,NSC 106404,Costunolid,(+)-Costunolide
Target: Apoptosis, Endogenous Metabolite, Telomerase
N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide
TN7036
Synonym: (9Z,12Z,15Z)-N-[(3-Methoxyphenyl)methyl]-9,12,15-octadecatrienamide,Macamide Impurity 14
Target: Wnt/beta-catenin
zerumbone
T5712
Synonym:
Target: Antioxidant, HSV
Rubone
T24744
Synonym:
Target:
Tetracycline hydrochloride
T0912
Synonym: NCI-c55561,Tetracycline HCl
Target: ribosome, Antibacterial, Antibiotic
(+)-Medicarpin
T13768
Synonym:
Target: Estrogen/progestogen Receptor
Tectorigenin
T3488
Synonym: 4',5,7-Trihydroxy-6-methoxyisoflavone,Tectorigenine
Target: Apoptosis
Veraguensin
TN1117
Synonym:
Target: p38 MAPK, NF-κB, Antibiotic, Parasite, Antifection
Glycitin
T2820
Synonym: Glycitein-7-β-O-glucoside,Glycitein 7-O-β-glucoside
Target: Others, Influenza Virus, Antibacterial
Dalbergin
TJS0856
Synonym: 6-Hydroxy-7-Methoxy-4-Phenylcoumarin
Target: Others
Poncirin
T3S2312
Synonym: Isosakuranetin-7-neohesperidoside
Target: Apoptosis, Others
Batilol
T3004
Synonym: Batilolum,Stearyl monoglyceride,Batyl alcohol,1-O-Octadecylglycerol
Target: Others, Endogenous Metabolite
H-HoArg-OH
T8103
Synonym:
Target: Endogenous Metabolite, Phosphorylase
Icariside I
T3808
Synonym: Lcariside I,Icariin I,Icarisid I
Target: Others
Methenolone enanthate
T9171
Synonym:
Target: Others
3-(3-Hydroxyphenyl)propionic Acid
T7437
Synonym: m-Hydroxyphenylpropionic acid,3-Hydroxyhydrocinnamic acid
Target: Others, Endogenous Metabolite
Metenolone acetate
T8117
Synonym: Methenolone acetate
Target: Others, Androgen Receptor
Chondroitin sulfate
T2980
Synonym: Chonsurid,Chondroitin polysulfate
Target: MMP, Others, Endogenous Metabolite, NO Synthase
Imperatorin
T2845
Synonym: Ammidin,8-Isoamylenoxypsoralen,8-Isopentenyloxypsoralene,Marmelosin,Pentosalen
Target: TRP/TRPV Channel, AChR, AChE, NOD
Curculigoside
T6S1966
Synonym: Curculigoside A
Target: Antioxidant, NF-κB, JAK, STAT
3′,4′,7-Trihydroxyflavone 
TN3209
Synonym:
Target: ATPase, Others, p38 MAPK, NF-κB
Gelsemine
T5S0662
Synonym: Gelsemin
Target: Antioxidant
Bavachalcone
T3S0137
Synonym:
Target: Antibacterial, Antibiotic
Astragaloside II
T3924
Synonym: Astrasieversianin VIII
Target: TGF-beta/Smad
Praeruptorin A
T3777
Synonym: (+)-Praeruptorin A
Target: CaMK, NF-κB
Gossypetin
TN1711
Synonym:
Target: Antioxidant, p38 MAPK, MAPK, Antibacterial
Dihydrolycorine
T3S1729
Synonym:
Target: Others
Neomangiferin
T3804
Synonym: Mangiferin 7-glucoside
Target: Phosphatase
Alisol B
T5770
Synonym:
Target: RANKL/RANK
Eleutheroside E
T3662
Synonym:
Target: NF-κB
Calcitriol
T6316
Synonym: Topitriol,Rocaltrol,Calcijex,RO215535,1,25-Dihydroxyvitamin D3
Target: Endogenous Metabolite
Medicarpin
TN1918
Synonym:
Target: Apoptosis, BCL, ROS, JNK
Soy Isoflavone
T8194L
Synonym:
Target: Others
Rubiadin-1-methyl ether
T4237
Synonym: Rubiadin 1-methyl ether
Target: Anti-infection, NF-κB
2-Furoic acid
T5544
Synonym: Furan-2-carboxylic acid
Target: Anti-infection, ATP Citrate Lyase, Endogenous Metabolite, Acyltransferase
Hydroxysafflor yellow A
T3674
Synonym: HSYA,Safflomin A
Target: TGF-beta/Smad
Asperosaponin VI
T2698
Synonym: Akebia saponin D,Asperosaponin Ⅵ
Target: Apoptosis, Others, Caspase
(2S)-2'-Methoxykurarinone
TN1215
Synonym: 2'-Methoxykurarinone,2'-O-Methylkurarinone
Target: Akt, Antifection
Methyl Vanillate
T2818
Synonym:
Target: Reactive Oxygen Species, Wnt/beta-catenin, Endogenous Metabolite
Raloxifene hydrochloride
T1549
Synonym: LY156758 hydrochloride,Raloxifene HCl,LY139481 hydrochloride,Keoxifene hydrochloride,LY156758 (Keoxifene) HCl
Target: Estrogen Receptor/ERR, Others, MAO, Estrogen/progestogen Receptor, Autophagy
Neobavaisoflavone
T6S0139
Synonym:
Target: Apoptosis, DNA/RNA Synthesis
ATP
T20089
Synonym: Atipi,ATP disodium salt hydrate,Triphosphoric acid adenosine ester,Ara-ATP,Triphosphaden,Adenosine triphosphate;Ara-ATP,Adenosine triphosphate
Target: Endogenous Metabolite
Pristimerin
T4S1050
Synonym: Celastrol methyl ester
Target: NF-κB, Antibacterial
L-Leucine
T3O2749
Synonym: (S)-Leucine,Leu
Target: mTOR

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-00680 BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant (hFc) Human,Mouse,Rat,Rhesus,Canine HEK293
BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokin...
TMPY-03235 BST2 Protein, Human, Recombinant (His) Human HEK293
BST2 was frequently overexpressed in GC tissues compared with the adjacent non-tumorous tissues, and high BST2 expression was correlated with tumor stage and lymphatic metastasis. Furthermore, in vitro experiments demons...
TMPY-00663 Alkaline Phosphatase/ALPL Protein, Human, Recombinant (His) Human HEK293
Alkaline phosphatase (ALPL) is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. The process of removing the phosphate group is cal...
TMPY-06842 BMP-4 Protein, Human, Recombinant (E399D) Human E. coli
BMP4 (bone morphogenetic protein-4)-directed differentiation of human embryonic stem cells (ESCd). Autophagy is a conserved catabolic process with complicated roles in tumor development. Bone morphogenetic protein 4 (BMP...
TMPY-03297 BMP-2 Protein, Danio rerio (zebrafish), Recombinant Danio rerio (zebrafish) E. coli
BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokin...
TMPY-00681 BMP-5 Protein, Human, Recombinant (hFc) Human HEK293
Bone Morphogenetic Protein 5 (BMP-5) is a member of the structurally and functionally related bone morphogenetic proteins (BMPs) which constitute a novel subfamily of the transforming growth factor β (TGF-β) superfamily....
TMPY-01059 BMPR2 Protein, Human, Recombinant (His) Human HEK293
The bone morphogenetic protein type II receptor (BMPR-II, or BMPR2), a receptor for the transforming growth factor (TGF)-beta/bone morphogenetic protein (BMP) superfamily. Reduced expression or function of BMPR2 signalin...
TMPY-01136 BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant Human,Mouse,Rat,Rhesus,Canine E. coli
BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokin...
TMPY-00614 BMPR1A/ALK-3 Protein, Canine, Recombinant (hFc) Canine HEK293
Activin receptor-Like Kinase 3 (ALK-3), also known as Bone Morphogenetic Protein Receptor, type IA (BMPR1A), is a type I receptor for bone morphogenetic proteins (BMPs) which belong to the transforming growth factor beta...
TMPY-03037 CD157 Protein, Rat, Recombinant (hFc) Rat HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-03038 CD157 Protein, Rat, Recombinant (His) Rat HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-00968 CD157 Protein, Human, Recombinant (His) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPJ-00924 Decorin Protein, Mouse, Recombinant (His) Mouse Human Cells
Decorin, also known as PG40 and DCN, is a member of the class I family of small leucine-rich proteoglycans (SLRPs) that is expressed in the stroma of various forms of cancer and has been recently proposed to act as a gua...
TMPJ-00445 IBSP Protein, Mouse, Recombinant (His) Mouse Human Cells
Bone sialoprotein 2(IBSP) is a monomeric non‑collagenous member of the SIBLING family of extracellular matrix proteins. It is principally associated with the early stages of bone mineralization. Mouse IBSP is synthesize...
TMPY-00431 BMP-4 Protein, Mouse, Recombinant (rFc) Mouse HEK293
BMP4 (bone morphogenetic protein-4)-directed differentiation of human embryonic stem cells (ESCd). Autophagy is a conserved catabolic process with complicated roles in tumor development. Bone morphogenetic protein 4 (BMP...
TMPY-03193 BST2 Protein, Human, Recombinant (hFc) Human HEK293
BST2 was frequently overexpressed in GC tissues compared with the adjacent non-tumorous tissues, and high BST2 expression was correlated with tumor stage and lymphatic metastasis. Furthermore, in vitro experiments demons...
TMPY-04367 BMPRIB Protein, Human, Recombinant (aa 149-502, His & GST) Human Baculovirus-Insect Cells
BMPR1B(bone morphogenetic protein receptor, type IB), also known as ALK6, is a member of the bone morphogenetic protein (BMP) receptor family. BMPs are involved in endochondral bone formation and embryogenesis. These pro...
TMPY-03362 BMPRIB Protein, Human, Recombinant (hFc) Human HEK293
BMPR1B(bone morphogenetic protein receptor, type IB), also known as ALK6, is a member of the bone morphogenetic protein (BMP) receptor family. BMPs are involved in endochondral bone formation and embryogenesis. These pro...
TMPY-00962 BMPR1A/ALK-3 Protein, Mouse, Recombinant (His & hFc) Mouse HEK293
Activin receptor-Like Kinase 3 (ALK-3), also known as Bone Morphogenetic Protein Receptor, type IA (BMPR1A), is a type I receptor for bone morphogenetic proteins (BMPs) which belong to the transforming growth factor beta...
TMPY-00594 Alkaline Phosphatase/ALPL Protein, Mouse, Recombinant (hFc) Mouse HEK293
Alkaline phosphatase (ALPL) is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. The process of removing the phosphate group is cal...
TMPY-00446 Alkaline Phosphatase/ALPL Protein, Mouse, Recombinant (His) Mouse HEK293
Alkaline phosphatase (ALPL) is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. The process of removing the phosphate group is cal...
TMPY-01374 BMPR1A/ALK-3 Protein, Mouse, Recombinant (His) Mouse HEK293
Activin receptor-Like Kinase 3 (ALK-3), also known as Bone Morphogenetic Protein Receptor, type IA (BMPR1A), is a type I receptor for bone morphogenetic proteins (BMPs) which belong to the transforming growth factor beta...
TMPY-01764 BMPR1A/ALK-3 Protein, Human, Recombinant (His) Human HEK293
Activin receptor-Like Kinase 3 (ALK-3), also known as Bone Morphogenetic Protein Receptor, type IA (BMPR1A), is a type I receptor for bone morphogenetic proteins (BMPs) which belong to the transforming growth factor beta...
TMPY-05485 BMPR1A/ALK-3 Protein, Human, Recombinant (hFc) Human HEK293
Activin receptor-Like Kinase 3 (ALK-3), also known as Bone Morphogenetic Protein Receptor, type IA (BMPR1A), is a type I receptor for bone morphogenetic proteins (BMPs) which belong to the transforming growth factor beta...
TMPJ-00713 GDF-11 Protein, Human, Recombinant Human Human Cells
Growth/differentiation factor 11(GDF-11) is a secreted protein, which belongs to the transforming growth factor beta superfamily. GDF-11 controls anterior-posterior patterning by regulating the expression of Hox genes. ...
TMPY-04742 BST2 Protein, Mouse, Recombinant (His) Mouse HEK293
BST2 was frequently overexpressed in GC tissues compared with the adjacent non-tumorous tissues, and high BST2 expression was correlated with tumor stage and lymphatic metastasis. Furthermore, in vitro experiments demons...
TMPJ-01473 BMP-7 Protein, Human, Recombinant Human Human Cells
Bone morphogenetic protein 7 (BMP7), also known as osteogenic protein-1 (OP-1) is a member of Transforming growth factor-β (TGF-β) family of proteins. Bone morphogenetic proteins were discovered in 1965 by Marshal Urist,...
TMPY-01178 CD157 Protein, Mouse, Recombinant (His) Mouse HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPK-00807 Osteopontin Protein, Mouse, Recombinant (His) Mouse HEK293
Secreted phosphoprotein 1 (SPP1) expression in TAMs isolated from lung adenocarcinoma tissues and PMA-treated THP-1 cells were measured. Macrophage polarization was identified by flow cytometric analysis. Cell migration ...
TMPY-02674 BST2 Protein, Mouse, Recombinant (hFc) Mouse HEK293
BST2 was frequently overexpressed in GC tissues compared with the adjacent non-tumorous tissues, and high BST2 expression was correlated with tumor stage and lymphatic metastasis. Furthermore, in vitro experiments demons...
TMPK-00538 Osteopontin Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Ovarian cancer is one of the most lethal malignant tumors in women. Secreted phosphoprotein 1 (SPP1) plays an important role in some cancer types. The expression of SPP1 was higher in epithelial ovarian cancer tissues th...
TMPK-00676 Osteopontin Protein, Human, Recombinant (aa 17-300, His) Human HEK293
Ovarian cancer is one of the most lethal malignant tumors in women. Secreted phosphoprotein 1 (SPP1) plays an important role in some cancer types. The expression of SPP1 was higher in epithelial ovarian cancer tissues th...
TMPJ-00476 BMPG Protein, Human, Recombinant (His) Human Human Cells
Bone Marrow Proteoglycan (BMPG) is a secreted protein that contains one C-type lectin domain. BMPG is the predominant constituent of the crystalline core of the eosinophil granule. BMPG is highly expressed in placenta an...
TMPY-04496 BMPRIB Protein, Mouse, Recombinant (hFc) Mouse HEK293
BMPR1B(bone morphogenetic protein receptor, type IB), also known as ALK6, is a member of the bone morphogenetic protein (BMP) receptor family. BMPs are involved in endochondral bone formation and embryogenesis. These pro...
TMPY-00683 BMPR2 Protein, Human, Recombinant (His & hFc) Human HEK293
The bone morphogenetic protein type II receptor (BMPR-II, or BMPR2), a receptor for the transforming growth factor (TGF)-beta/bone morphogenetic protein (BMP) superfamily. Reduced expression or function of BMPR2 signalin...
TMPJ-00202 CD157 Protein, Human, Recombinant (hFc) Human Human Cells
The cluster of differentiation (CD) system is a glycosyl phosphatidylinositol anchored membrane protein that belongs to the CD38 family.It is generally used in immunophynotyping. CD157 was discovered in a bone marrow str...
TMPJ-00325 BMPR1A/ALK-3 Protein, Human, Recombinant (hFc & His) Human Human Cells
Bone Morphogenetic Protein Receptor Type-1A (BMPR1A) belongs to the TKL Ser/Thr protein kinase family and TGFB receptor subfamily, including the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. BMPR1A i...
TMPJ-00966 GDF-5 Protein, Human, Recombinant Human E. coli
Growth Differentiation Factor 5(GDF-5, BMP-14) is a member of the BMP family of TGFβ superfamily proteins. Human GDF-5, -6, and -7 are a defined subgroup of the BMP family. GDF-5 is synthesized as a homodimeric precursor...
TMPY-01633 SOST Protein, Rat, Recombinant (His) Rat HEK293
Sclerostin, the protein product of the SOST gene, is a potent inhibitor of bone formation. Sclerostin protein is widely expressed at low levels with highest levels in bone, cartilage, kidney, liver, bone marrow and prima...
TMPY-00925 SOST Protein, Human, Recombinant (His) Human HEK293
Sclerostin, the protein product of the SOST gene, is a potent inhibitor of bone formation. Sclerostin protein is widely expressed at low levels with highest levels in bone, cartilage, kidney, liver, bone marrow and prima...
TMPY-04142 RANK/TNFRSF11A Protein, Human, Recombinant (hFc) Human HEK293
TNFRSF11A is a member of the TNF-receptor superfamily. In mouse, it is also known as CD265. TNFRSF11A contains 4 TNFR-Cys repeats and is widely expressed with high levels in skeletal muscle, thymus, liver, colon, small i...
TMPY-03674 RANKL/TNFSF11/CD254 Protein, Human, Recombinant (mFc) Human HEK293
Tumor necrosis factor ligand superfamily member 11, also known as Receptor activator of nuclear factor kappa-B ligand, Osteoprotegerin ligand, TNFSF11, RANKL, TRANCE, OPGL and CD254, is a single-pass type II membrane pro...
TMPY-02726 RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (hFc) Mouse HEK293
Tumor necrosis factor ligand superfamily member 11, also known as Receptor activator of nuclear factor kappa-B ligand, Osteoprotegerin ligand, TNFSF11, RANKL, TRANCE, OPGL and CD254, is a single-pass type II membrane pro...
TMPY-03364 RANKL/TNFSF11/CD254 Protein, Human, Recombinant Human HEK293
Tumor necrosis factor ligand superfamily member 11, also known as Receptor activator of nuclear factor kappa-B ligand, Osteoprotegerin ligand, TNFSF11, RANKL, TRANCE, OPGL and CD254, is a single-pass type II membrane pro...
TMPJ-01172 IL-17 Protein, Mouse, Recombinant (His) Mouse Human Cells
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Mature mouse IL-17A shares 61% and 89% amino acid seque...
TMPY-00890 Noggin/NOG Protein, Human, Recombinant (hFc) Human HEK293
Noggin is a secreted protein involved at multiple stages of vertebrate embryonic development including neural induction and is known to exert its effects by inhibiting the bone morphogenetic protein (BMP)-signaling pathw...
TMPY-05202 Noggin/NOG Protein, Human, Recombinant Human HEK293
Noggin is a secreted protein involved at multiple stages of vertebrate embryonic development including neural induction and is known to exert its effects by inhibiting the bone morphogenetic protein (BMP)-signaling pathw...
TMPY-02594 Noggin/NOG Protein, Mouse, Recombinant (hFc) Mouse HEK293
Noggin is a secreted protein involved at multiple stages of vertebrate embryonic development including neural induction and is known to exert its effects by inhibiting the bone morphogenetic protein (BMP)-signaling pathw...
TMPY-01009 TGFBI Protein, Human, Recombinant (His) Human HEK293
TGFBI is an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several ...
TMPJ-01470 SCF Protein, Human, Recombinant Human E.coli
Stem Cell Factor (SCF) is a hematopoietic growth factor that exerts its activity at the early stages of hematopoiesis. SCF stimulates the proliferation of myeloid, erythroid, and lymphoid progenitors in bone marrow cultu...
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BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant (hFc)
TMPY-00680
Species: Human,Mouse,Rat,Rhesus,Canine
Expression System: HEK293
BST2 Protein, Human, Recombinant (His)
TMPY-03235
Species: Human
Expression System: HEK293
Alkaline Phosphatase/ALPL Protein, Human, Recombinant (His)
TMPY-00663
Species: Human
Expression System: HEK293
BMP-4 Protein, Human, Recombinant (E399D)
TMPY-06842
Species: Human
Expression System: E. coli
BMP-2 Protein, Danio rerio (zebrafish), Recombinant
TMPY-03297
Species: Danio rerio (zebrafish)
Expression System: E. coli
BMP-5 Protein, Human, Recombinant (hFc)
TMPY-00681
Species: Human
Expression System: HEK293
BMPR2 Protein, Human, Recombinant (His)
TMPY-01059
Species: Human
Expression System: HEK293
BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant
TMPY-01136
Species: Human,Mouse,Rat,Rhesus,Canine
Expression System: E. coli
BMPR1A/ALK-3 Protein, Canine, Recombinant (hFc)
TMPY-00614
Species: Canine
Expression System: HEK293
CD157 Protein, Rat, Recombinant (hFc)
TMPY-03037
Species: Rat
Expression System: HEK293
CD157 Protein, Rat, Recombinant (His)
TMPY-03038
Species: Rat
Expression System: HEK293
CD157 Protein, Human, Recombinant (His)
TMPY-00968
Species: Human
Expression System: HEK293
Decorin Protein, Mouse, Recombinant (His)
TMPJ-00924
Species: Mouse
Expression System: Human Cells
IBSP Protein, Mouse, Recombinant (His)
TMPJ-00445
Species: Mouse
Expression System: Human Cells
BMP-4 Protein, Mouse, Recombinant (rFc)
TMPY-00431
Species: Mouse
Expression System: HEK293
BST2 Protein, Human, Recombinant (hFc)
TMPY-03193
Species: Human
Expression System: HEK293
BMPRIB Protein, Human, Recombinant (aa 149-502, His & GST)
TMPY-04367
Species: Human
Expression System: Baculovirus-Insect Cells
BMPRIB Protein, Human, Recombinant (hFc)
TMPY-03362
Species: Human
Expression System: HEK293
BMPR1A/ALK-3 Protein, Mouse, Recombinant (His & hFc)
TMPY-00962
Species: Mouse
Expression System: HEK293
Alkaline Phosphatase/ALPL Protein, Mouse, Recombinant (hFc)
TMPY-00594
Species: Mouse
Expression System: HEK293
Alkaline Phosphatase/ALPL Protein, Mouse, Recombinant (His)
TMPY-00446
Species: Mouse
Expression System: HEK293
BMPR1A/ALK-3 Protein, Mouse, Recombinant (His)
TMPY-01374
Species: Mouse
Expression System: HEK293
BMPR1A/ALK-3 Protein, Human, Recombinant (His)
TMPY-01764
Species: Human
Expression System: HEK293
BMPR1A/ALK-3 Protein, Human, Recombinant (hFc)
TMPY-05485
Species: Human
Expression System: HEK293
GDF-11 Protein, Human, Recombinant
TMPJ-00713
Species: Human
Expression System: Human Cells
BST2 Protein, Mouse, Recombinant (His)
TMPY-04742
Species: Mouse
Expression System: HEK293
BMP-7 Protein, Human, Recombinant
TMPJ-01473
Species: Human
Expression System: Human Cells
CD157 Protein, Mouse, Recombinant (His)
TMPY-01178
Species: Mouse
Expression System: HEK293
Osteopontin Protein, Mouse, Recombinant (His)
TMPK-00807
Species: Mouse
Expression System: HEK293
BST2 Protein, Mouse, Recombinant (hFc)
TMPY-02674
Species: Mouse
Expression System: HEK293
Osteopontin Protein, Cynomolgus, Recombinant (His)
TMPK-00538
Species: Cynomolgus
Expression System: HEK293
Osteopontin Protein, Human, Recombinant (aa 17-300, His)
TMPK-00676
Species: Human
Expression System: HEK293
BMPG Protein, Human, Recombinant (His)
TMPJ-00476
Species: Human
Expression System: Human Cells
BMPRIB Protein, Mouse, Recombinant (hFc)
TMPY-04496
Species: Mouse
Expression System: HEK293
BMPR2 Protein, Human, Recombinant (His & hFc)
TMPY-00683
Species: Human
Expression System: HEK293
CD157 Protein, Human, Recombinant (hFc)
TMPJ-00202
Species: Human
Expression System: Human Cells
BMPR1A/ALK-3 Protein, Human, Recombinant (hFc & His)
TMPJ-00325
Species: Human
Expression System: Human Cells
GDF-5 Protein, Human, Recombinant
TMPJ-00966
Species: Human
Expression System: E. coli
SOST Protein, Rat, Recombinant (His)
TMPY-01633
Species: Rat
Expression System: HEK293
SOST Protein, Human, Recombinant (His)
TMPY-00925
Species: Human
Expression System: HEK293
RANK/TNFRSF11A Protein, Human, Recombinant (hFc)
TMPY-04142
Species: Human
Expression System: HEK293
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (mFc)
TMPY-03674
Species: Human
Expression System: HEK293
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (hFc)
TMPY-02726
Species: Mouse
Expression System: HEK293
RANKL/TNFSF11/CD254 Protein, Human, Recombinant
TMPY-03364
Species: Human
Expression System: HEK293
IL-17 Protein, Mouse, Recombinant (His)
TMPJ-01172
Species: Mouse
Expression System: Human Cells
Noggin/NOG Protein, Human, Recombinant (hFc)
TMPY-00890
Species: Human
Expression System: HEK293
Noggin/NOG Protein, Human, Recombinant
TMPY-05202
Species: Human
Expression System: HEK293
Noggin/NOG Protein, Mouse, Recombinant (hFc)
TMPY-02594
Species: Mouse
Expression System: HEK293
TGFBI Protein, Human, Recombinant (His)
TMPY-01009
Species: Human
Expression System: HEK293
SCF Protein, Human, Recombinant
TMPJ-01470
Species: Human
Expression System: E.coli
Cat No. Product Name
L7900 Osteogenesis Compound Library

320 compounds
A unique collection of 320 osteogenesis related compounds for high throughput and high content screening;
L8400 Hematonosis Compound Library

524 compounds
A unique collection of 524 compounds related to hematologic diseases for high throughput screening (HTS) and high content screening (HCS);
L9810 Anti-Fibrosis Compound Library

1180 compounds
A unique collection of 1180 potential anti-fibrosis compounds, can be used in HTS and HCS;
L6230 Miao medicine Compound Library

540 compounds
A unique collection of 540 compounds featuring natural product molecules derived from Miao medicine that can be used for high-throughput and high-content screening.
L8000 Stem Cell Differentiation Compound Library

1213 compounds
A unique collection of 1213 stem cell differentiation signaling targeted compounds for high throughput and high content screening;
TargetMol