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bi-3406

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  • Inhibitors & Agonists
    2
    TargetMol | Inhibitors_Agonists
BI-3406
T129792230836-55-0
BI-3406 is an orally active, highly potent and selective between KRAS and Son of Sevenless 1 (SOS1) interaction inhibitor(IC50 : 6 nM),with anticancer activity.
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SOS1-IN-14
T638872793405-20-4
SOS1-IN-14 is a selective, potent, orally active SOS1 inhibitor (IC50: 3.9 nM). sOS1-IN-14 is absorbed in the intestine using a P-glycoprotein-mediated efflux mechanism. sOS1-IN-14 can be used in the study of KRAS mutated cancers and is more effective in tumour suppression than BI-3406.
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8-10 weeks
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