bap1

BAP1-IN-1 is an inhibitor of the catalytic activity of BRCA1-associated protein 1 (BAP1), which is related to cancer and can be used to study cancer.

TG2-179-1 is a BRCA1-associated protein 1 (BAP1) inhibitor with potential anticancer activity. TG2-179-1 exhibits potent cytotoxic activity against colon cancer cells and induces apoptosis. TG2-179-1 can be used in colon cancer research. TG2-179-1 is a BRCA1-associated protein 1 (BAP1) inhibitor with potential anticancer activity.

B-AP15 (NSC-687852)(NSC-687852) is a selective inhibitor of the deubiquitinating enzymes Usp14 and UCHL5 of the 26S proteasome. It blocks the deubiquitinating activity of the 26S proteasome.

VLX 1500 is a potent deubiquitinating enzyme (DUBs) inhibitor designed to overcome resistance to traditional proteasome inhibitors. It triggers ER stress-mediated apoptosis by specifically blocking USP14/UCHL5 activity on the 19S regulatory particle, leading to a lethal accumulation of ubiquitinated proteins, widely used in drug target screening for relapsed hematological malignancies.

LN-439A (compound LN-439A) is a novel BAP1 inhibitor that suppresses the growth of basal-like breast cancer by degrading KLF5.