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artd10

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    5
    TargetMol | Inhibitors_Agonists
  • Recombinant Protein
    1
    TargetMol | Recombinant_Protein
ARTD10/PARP10-IN-1
T725531708103-76-7
ARTD10 PARP10-IN-1 is a potent PARP inhibitor of the mono-ADP ribosyltransferases ARTD7 PARP15, ARTD8 PARP14, ARTD10 PARP10 and poly ADP-ribose polymerase-1 (ARTD1 PARP1), with potential anticancer and antitumour activity for the study of prostate and breast cancers.
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6-8 weeks
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artd10/parp10-in-2
T725541708103-69-8
ARTD10 PARP10-IN-2 is a potent, non-selective inhibitor of mono-ADP-ribosyltransferases ARTD10 PARP10 and poly(ADP-ribose) polymerase-1 ARTD1 PARP1, exhibiting IC50 values of 2.0 μM and 9.7 μM, respectively.
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6-8 weeks
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ME0328
T65781445251-22-8
ME0328 is a potent, selective PARP inhibitor with an IC50 of 0.89 μM for PARP3, showing approximately 7-fold selectivity over PARP1.
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YCH1899
T79667
YCH1899, an orally active PARP inhibitor, demonstrates potent inhibition of PARP1 2 with an IC50 of less than 0.001 nM. It shows marked antiproliferative efficacy against Olaparib-resistant (Capan-1 OP) and Talazoparib-resistant (Capan-1 TP) cells with IC50 values of 0.89 nM and 1.13 nM, respectively. Moreover, YCH1899 possesses favorable pharmacokinetic attributes in rats [1].
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OUL35
NSC39047
T90246336-34-1
OUL35 (NSC-39047) is a selective PARP-10 inhibitor, and small-molecule ARTD10 inhibitor. OUL35 has been shown to rescue cells from ARTD10-induced cell death.
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