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  • Apoptosis
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apoptosis, in gbm cscs

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  • Inhibitors & Agonists
    3
    TargetMol | Inhibitors_Agonists
RIPGBM
T16754355406-76-7
RIPGBM is a selective inducer of apoptosis in glioblastoma multiforme cancer stem cells (EC50: ≤500 nM).
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cRIPGBM
T192502361988-76-1
cRIPGBM, a proapoptotic derivative of RIPGBM, selectively induces apoptosis in GBM cancer stem cells (CSCs) by targeting receptor-interacting protein kinase 2 (RIPK2), demonstrating an EC50 of 68 nM in GBM-1 cells [1].
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6-8 weeks
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GBM CSCs-IN-1
T200175
GBM CSCs-IN-1 (Compound (−)-20), a rocaglate derivative, potently inhibits glioblastoma stem cells (GBM CSCs) and exhibits an EC50 of 45 nM by targeting the RNA helicase DDX3. Additionally, it induces apoptosis in these cells.
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