Home Tools
Log in
Cart

Search Result

Search Results for " antiprion "

9

Compounds

Cat No. Product Name Synonyms Targets
T23450 TCS PrP Inhibitor 13 5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One Others
TCS PrP Inhibitor 13 (5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One) is an antiprion agent inhibiting protease-resistant prion protein (PrP-res) accumulation.
T25532 IND81 IND-81,IND 81
IND81 is an antiprion agent that works by extending the lives of prion-infected animals.
T27605 IND45193 IND-45193,IND 45193
IND45193, an antiprion agent, acts by reducing PrP(Sc) levels in dividing and stationary-phase cells.
T11801 L-Atabrine dihydrochloride Others
l-Atabrine dihydrochloride displays antiprion activity. l-Atabrine dihydrochloride is a less active enantiomer of quinacrine.
T61651 Quinoprazine
Quinoprazine, a powerful inhibitor of Vaccinia virus DNA synthesis (IC50 = 10 μM), exhibits notable antimalarial activity against Plasmodium berghei. Additionally, it demonstrates significant antiprion potency, effective...
T38146 Chloroguanabenz (acetate)
Chloroguanabenz is an antiprion agent and a derivative of the α2-adrenergic receptor agonist guanabenz . It inhibits prion formation in yeast and mammalian cell-based assays. Chloroguanabenz reduces the levels of both so...
T73416 BiCAPPA
BiCAPPA, a pioneering bivalent antiprion ligand, effectively reduces the infectious conformational form of prion protein (PrP Sc) in scrapie-infected cells, achieving this at a concentration (EC 50) of 0.32 μM.
T38186 6-Amino-8-trifluoromethylphenanthridine
6-Amino-8-trifluoromethylphenanthridine (6A-8tFP) is an antiprion agent and a derivative of 6-aminophenanthridine . It inhibits protein folding activity of the ribosome (PFAR) when used at a concentration of 150 μM. 6A-8...
T38187 6-Aminophenanthridine
6-Aminophenanthridine is an antiprion agent. It inhibits prion formation in yeast- and mammalian-based screening assays when used alone and, to a greater extent, when used in combination with the α2-adrenergic receptor a...
TargetMol