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By Target- IFNAR
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Results for "
anifrolumab
" in TargetMol Product Catalog- Inhibitors & Agonists2
- Inhibitory Antibodies2
Anifrolumab
MEDI-546, MDX-1333
T774321326232-46-5
Anifrolumab(MEDI-546) is a potent type I interferon (IFN) receptor antagonist, a human monoclonal antibody that targets IFN.Anifrolumab inhibits the activity of type I interferon and is used for the prevention and treatment of systemic lupus erythematosus (SLE).
- $197
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QTY
Anti-IFNAR1 Antibody
T9901A-1269
Anti-IFNAR1 Antibody (Anifrolumab) is a humanized IgG1 kappa monoclonal antibody targeting the type I interferon receptor subunit 1 (IFNAR1). This product specifically binds to IFNAR1, blocking the interaction of all type I interferons (including all subtypes of IFN-alpha, IFN-beta, and IFN-omega) with the receptor complex. This inhibition blocks the activation of the downstream JAK/STAT signaling pathway, reduces the expression of interferon-stimulated genes (ISGs), and suppresses type I interferon-mediated immune responses.
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