aminopterin

Aminopterin (4-Aminofolic acid) is a synthetic folic acid derivative whose metabolite is a competitive inhibitor of dihydrofolate reductase

10-Deazaaminopterin is a poly-gamma-glutamyl metabolite of the experimental anticancer drug, a folic acid antagonist, antineoplastic agent enzyme inhibitor.

Aminopterin N-hydroxysuccinimide ester is an antineoplastic agent with immunosuppressive properties. Aminopterin works as an enzyme inhibitor by competing for the folate binding site of the enzyme dihydrofolate reductase. Its binding affinity for dihydrof

Aminopterin sodium is an antineoplastic agent with immunosuppressive properties. Aminopterin works as an enzyme inhibitor by competing for the folate binding site of the enzyme dihydrofolate reductase. Its binding affinity for dihydrofolate reductase effe

Aminopterin (Standard) is a reference standard for research and analysis in studies involving Aminopterin. Aminopterin (4-Aminofolic acid) is a synthetic folic acid derivative whose metabolite is a competitive inhibitor of dihydrofolate reductase

Dihydroaminopterin is a derivative of aminopterin.

10-Methyl-10-deazaaminopterin, a folate analog, exhibits antitumor activity.

11-Oxahomoaminopterin exhibits antifolate activity against two folate-requiring microorganisms and inhibited Lactobacillus casei DHFR.

2'-Fluoroaminopterin is a folic acid antagonist agent.

3'-Fluoroaminopterin is a folic acid antagonist agent.

5,10-Dideazaaminopterin is an antileukemic drug.

11-Thiohomoaminopterin is a 11-thiohomofolic acid analog.

Deazaminopterin is a bioactive chemical.

Tetrahydroxyaminopterin is a bioactive chemical.

Pralatrexate (10-Propargyl-10-deazaaminopterin) is a folate analogue inhibitor of dihydrofolate reductase (DHFR) exhibiting high affinity for reduced folate carrier-1 (RFC-1) with antineoplastic and immunosuppressive activities.

Deamino-pterinotoxin-1 is a polypeptide toxin synthesized by the deamination of pterinotoxin-1.

Furterene is a diuretic from the aminopterin series with anti-aldosterone properties. It works by antagonizing aldosterone at the mineralocorticoid receptors in the kidneys, leading to increased sodium excretion while reducing potassium excretion.

NSC 184692 is a aminopterin-derivative.

Talotrexin (PT523), an analog of Aminopterin, is a nonpolyglutamatable classic antifolate that specifically inhibits the reduced folate carrier (RFC), selectively impeding RFC transport and targeting dihydrofolate reductase (DHFR) to demonstrate antitumor activity and inhibit tumor growth [1] [2].