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amd3465

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  • Inhibitors & Agonists
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AMD 3465
GENZ-644494
T14208185991-24-6
AMD 3465 also potently inhibits the replication of X4 HIV strains (IC50: 1-10 nM). However, it has no effect on CCR5-using (R5) viruses. AMD 3465 (GENZ-644494) is a potent antagonist of CXCR4, inhibits binding of 12G5 mAb and CXCL12AF647 to CXCR4, with IC
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6-8 weeks
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AMD 3465 hexahydrobromide
GENZ-644494 (hexahydrobromide)
T7208185991-07-5
AMD 3465 hexahydrobromide (GENZ-644494 (hexahydrobromide)) is a CXCR4 receptor antagonist with potential anticancer and anti-HIV activity.
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